摘要
目的探讨早发型重度子痫前期患者不同终止妊娠时机、分娩方式对母婴结局的影响。方法回顾性分析2014年1月至2020年6月江苏省无锡市妇幼保健院收治86例早发型重度子痫前期患者的临床资料,根据不同的终止妊娠时间分为A组(27例、终止妊娠时间<32周),B组(31例、终止妊娠时间32~34周),C组(28例、终止妊娠时间>34周);根据分娩方式将其分为阴道分娩组(35例)及剖宫产组(51例)。比较各组孕期并发症以及围生儿结局。结果B、C组发病孕龄大于A组,C组发病孕龄大于B组,差异有统计学意义(P<0.05);C组保守治疗时间短于B组,B组保守治疗时间长于A组,差异有统计学意义(P<0.05)。三组孕期并发症总发生率比较,差异无统计学意义(P>0.05)。B、C组围生儿死亡率、新生儿窒息率低于A组,Apgar评分高于A组,差异有统计学意义(P<0.05);C组出生体重高于A、B组,B组出生体重高于A组,差异有统计学意义(P<0.05)。剖宫产组围生儿死亡、胎儿窘迫及新生儿窒息发生率低于阴道分娩组,Apgar评分高于阴道分娩组,差异有统计学意义(P<0.05)。结论在保障安全的前提下延长早发型重度子痫前期患者孕龄至34周以上对母婴结局较好,并提高新生儿存活质量。另外合理采用剖宫产分娩方式能有效降低围生儿死亡率和新生儿窒息发生率。
Objective To explore the effect of different timing of pregnancy termination and mode of delivery on maternal and infant outcome in patients with early onset severe preeclampsia.Methods The clinical data of 86 patients with early onset severe preeclampsia admitted to Wuxi Eighth People’s Hospital from January 2014 to June 2020 were retrospectively analyzed.According to different timing of pregnancy termination,they were divided into group A(27 cases,timing of pregnancy termination<32 weeks),group B(31 cases,timing of pregnancy termination was 32-34 weeks),and group C(28 cases,timing of pregnancy termination>34 weeks);according to the mode of delivery,they were divided into vaginal delivery group(35 cases)and cesarean section group(51 cases).The complications and perinatal outcomes were compared in each groups.Results The onset of gestational age of group B and group C were greater than those of group A,and the onset of gestational age of group C was greater than that of group B,and the differences were statistically significant(P<0.05).The duration of conservative treatment in group C was shorter than that in group B,and the duration of conservative treatment in group B was longer than that in group A,and the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of pregnancy complications among three groups(P>0.05).The rate of perinatal mortality and neonatal asphyxia in group B and group C were lower than those in group A,and Apgar score was higher than that in group A,and the differences were statistically significant(P<0.05).The birth weight of group C was higher than that of group A and group B,and the birth weight of group B was higher than that of group A,and the differences were statistically significant(P<0.05).The rate of perinatal mortality,fetal distress and neonatal asphyxia in cesarean section group were lower than those in vaginal delivery group,and Apgar score was higher than that in vaginal delivery group,and the differences were statistica
作者
张珂
杨一新
张波
ZHANG Ke;YANG Yixin;ZHANG Bo(Department of Gynecology and Obstetrics,Wuxi Eighth People’s Hospital,Jiangsu Province,Wuxi 214000,China;Department of Gynecology and Obstetrics,Wuxi Maternal and Child Health Care Hospital,Jiangsu Province,Wuxi 214000,China)
出处
《中国医药导报》
2021年第24期92-95,共4页
China Medical Herald
基金
江苏省高等学校自然科学研究面上项目(18KJB320010)。
关键词
早发型重度子痫前期
终止妊娠
分娩方式
母婴结局
Early onset severe preeclampsia
Pregnancy termination
Mode of delivery
Maternal and infant outcome