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牺牲模板法制备PCL支架及性能研究

Study on Preparation and Performance of PCL Scaffold by Sacrificial Template Method
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摘要 使用3D打印机制备不同参数的聚乙烯醇(PVA)模板,结合牺牲模板技术制备聚己内酯(PCL)支架,研究模板参数孔隙率和压缩强度的影响。结果表明:支架具有超过95%的孔隙率,堆叠角度、打印层厚对支架的孔隙率影响不大,但是随填充密度的增加,孔隙率略有降低。力学性能方面,随着填充密度的升高、打印层厚的降低,支架的压缩强度提高;相同填充密度、打印层厚下,0°/90°堆叠有最高的力学强度,0°/45°/90°/135°次之,0°/60°/120°强度最差。 Polyvinyl alcohol(PVA)templates with different parameters were prepared by 3D printer,and polycaprolactone(PCL)scaffolds were prepared by sacrificial template technology.The effects of template parameters on porosity and compressive strength were studied.The results showed that the porosity of the scaffold was more than 95%.The stacking angle and print layer thickness had little effect on the porosity of the scaffold,but the porosity decreased slightly with the increase of filling density.In terms of mechanical properties,the compressive strength of the scaffold increased with the increase of filling density and the decrease of print layer thickness.Under the same filling density and print layer thickness,0°/90°stacking had the highest mechanical strength,0°/45°/90°/135°took the second place,0°/60°/120°was the worst.
作者 刘航 陈小红 LIU Hang;CHEN Xiao-hong(School of Materials Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China)
出处 《广州化工》 CAS 2021年第16期32-35,共4页 GuangZhou Chemical Industry
基金 国家自然科学基金资助项目(No.51201107)。
关键词 组织支架 3D打印 力学性能 压缩强度 tissue scaffold 3D printing mechanical properties compressive strength
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