摘要
目的探讨血清鳞状细胞癌抗原在几种常见皮肤病中的检测价值。方法收集2019年3月-2021年1月在中山大学孙逸仙纪念医院皮肤科病区住院的389例患者临床资料,分析血清SCC-Ag水平及36例皮肤病患者治疗前后的SCC-Ag水平。结果常见皮肤病SCC-Ag阳性率自低到高依次为天疱疮(61.29%)、大疱型类天疱疮(62.96%)、药疹(72.22%)、湿疹(72.34%)、银屑病(89.29%)、红皮病(100.00%);其它常见皮肤病SCC-Ag阳性主要以接触性皮炎为主。36例皮肤病患者治疗时间为3~15 d,治疗后血清SCC-Ag阳性率、SCC-Ag水平低于治疗前,差异有统计学意义(P<0.05)。结论血清SCC-Ag检测可以作为皮肤病诊断、皮损脱屑程度和治疗效果监测的一项指标。
Objective To investigate the expression of serum squamous cell carcinoma antigen in several common skin diseases.Methods The clinical data of 389 patients hospitalized in the Dermatology Ward of Sun Yat-sen Memorial Hospital of Sun Yat-sen University from March 2019 to January 2021 were collected,and the serum SCC-Ag levels and the SCC-Ag levels of 36 patients with skin diseases before and after treatment were analyzed.Results The SCC-Ag positive rate of common skin diseases in descending order was pemphigus(61.29%),bullous pemphigoid(62.96%),drug eruption(72.22%),eczema(72.34%),and psoriasis.(89.29%),erythroderma(100.00%);Other common skin diseases SCC-Ag positive are mainly contact dermatitis.The treatment time of 36 patients with skin diseases was 3-15 d.After treatment,the positive rate of serum SCC-Ag and the level of SCC-Ag were lower than before treatment,the difference was statistically significant(P<0.05).Conclusion Serum SCC-Ag detection can be used as an indicator for the diagnosis of skin diseases,the degree of scaling of skin lesions and the monitoring of treatment effects.
作者
熊戌霞
蔡梦珊
吴文钦
XIONG Xu-xia;CAI Meng-shan;WU Wen-qin(Department of Laboratory Medicine,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510000,Guangdong,China)
出处
《医学信息》
2021年第17期181-183,共3页
Journal of Medical Information
关键词
鳞状细胞癌抗原
皮肤病
红皮病
银屑病
Squamous cell carcinoma antigen
Skin disease
Erythroderma
Psoriasis
