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银屑病患者血清鳞状细胞癌抗原测定 被引量:3

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摘要 目的:测定银屑病患者血清鳞状细胞癌抗原(SCC-Ag)水平,探讨其在银屑病患者中的临床表达及意义。方法:收集浙江大学医学院附属第二医院皮肤科2011年11月-2013年7月收治的124例银屑病患者,按照疾病类型分为4组患者(寻常型银屑病58例,红皮病型银屑病23例,关节病型银屑病21例,脓疱型银屑病22例),采用微粒子酶联免疫吸附法对所有患者血清SCC-Ag水平进行检测,比较不同SCCAg水平对不同类型银屑病的诊断价值。结果:124例银屑病患者血清SCC-Ag浓度较正常值均升高,其中以红皮病型银屑病患者的血清SCC-Ag浓度最高(47.36±22.79)ng/ml,关节病型银屑病最低(5.20±3.07)ng/ml,4种类型患者与正常值比较差异具有统计学意义(P<0.05)。结论:银屑病患者血清SCC-Ag浓度普遍较高,是银屑病疾病严重程度的标志之一,可作为临床工作中银屑病治疗效果评价的一项参考指标。
出处 《中国高等医学教育》 2014年第6期120-121,共2页 China Higher Medical Education
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