摘要
目的探讨针灸结合中药对帕金森病患者运动及认知功能的影响。方法选取我院2017年4月至2019年11月收治的94例帕金森病患者作为研究对象,采用随机数字表法将其分为对照组(n=47)与研究组(n=47)。对照组给予西医药物治疗,研究组给予针灸结合中药治疗。比较两组的运动及认知功能评分、炎性因子水平、不良反应发生情况。结果治疗后,两组的UPDRS-Ⅲ评分均降低,MMSE及MoCA评分均升高,且研究组优于对照组(P<0.05)。治疗后,两组的TNF-α、hs-CRP及IL-6水平均降低,且研究组低于对照组(P<0.05)。研究组的不良反应总发生率为4.26%,低于对照组的17.02%(P<0.05)。结论针灸结合中药治疗帕金森病可改善患者的运功及认知功能,减轻机体炎症反应,且安全性较高。
Objective To explore the effects of acupuncture combined with traditional Chinese medicine on motor and cognitive functions in patients with Parkinson's disease.Methods Ninety-four patients with Parkinson's disease treated in our hospital from April 2017 to November 2019 were selected as the research objects and divided into control group(n=47)and study group(n=47)according to the random number table method.The control group was treated with western medicine,and the study group was treated with acupuncture combined with traditional Chinese medicine.The scores of motor and cognitive functions,levels of inflammatory factors and incidence of adverse reactions were compared between the two groups.Results After treatment,the UPDRS-Ⅲscore of the two groups decreased,the MMSE and MoCA scores increased,and those of the study group were better than the control group(P<0.05).After treatment,the levels of TNF-α,hs-CRP and IL-6 in the two groups decreased,and those in the study group were lower than the control group(P<0.05).The total incidence of adverse reactions in the study group was 4.26%,which was lower than 17.02% in the control group(P<0.05).Conclusion Acupuncture combined with traditional Chinese medicine in the treatment of Parkinson's disease can improve the motor and cognitive functions of patients,reduce the inflammatory reaction of the body,with high safety.
作者
樊飞
马欣波
FAN Fei;MA Xinbo(Sun Simiao Hospital of BUCM,Tongchuan 727000;the Second Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)
出处
《临床医学研究与实践》
2021年第24期145-147,共3页
Clinical Research and Practice
关键词
针灸
中药
帕金森病
运动功能
认知功能
acupuncture
traditional Chinese medicine
Parkinson's disease
motor function
cognitive function
