摘要
采用中红外(MIR)光谱开展了泰斯花粉阻隔剂(以下简称泰斯)及白凡士林的分子结构的研究,泰斯及白凡士林分子的红外吸收模式主要包括:νasCH3、νsCH3、νasCH2、νsCH2、δasCH3、δsCH3、δCH2和γCH2。在泰斯及白凡士林分子的变温中红外(TD-MIR)光谱研究中发现:随着测定温度的升高(293 K~433 K),泰斯及白凡士林分子主要官能团对应的红外吸收频率及强度均有所改变。最后采用二维中红外(2D-MIR)光谱进一步开展泰斯及白凡士林热稳定性的研究,研究发现:泰斯与白凡士林的分子结构高度一致,均为高碳烷烃,但白凡士林分子中高碳烷烃的碳链长度要略大于泰斯分子中高碳烷烃的碳链长度。本项研究拓展了三级MIR光谱在重要的医药(泰斯)分子结构及热稳定性的研究范围。
The molecular structure of Taisi pollen barrier(Taisi)and white vaseline was studied by mid infrared(MIR)spectroscopyνasCH3、νsCH3、νasCH2、νsCH2、δasCH3、δsCH3、δCH2 andγCH2.It was found that the infrared absorption frequency and intensity of the main functional groups of Taisi and white vaseline changed with the increase of temperature(293 K~433 K).Finally,two-dimensional mid infrared(2d-mir)spectroscopy was used to further study the thermal stability of Taisi and white vaseline.It was found that the molecular structures of Taisi and white vaseline were highly consistent.They were all high carbon alkanes,but the carbon chain length of high carbon alkanes in white vaseline was slightly longer than that of high carbon alkanes in Tess.This study expanded the scope of three-level MIR spectroscopy in the study of important pharmaceutical(Taisi)molecular structure and thermal stability.
作者
于宏伟
王晓萱
戎媛
康怡然
李佳欣
卫羽萱
YU Hong-wei;WANG Xiao-xuan;RONG Yuan;KANG Yi-ran;LI Jia-xin;WEI Yu-xuan(School of Chemical Engineering,Shijiazhuang University,Shijiazhuang 050035,China)
出处
《佛山科学技术学院学报（自然科学版）》
CAS
2021年第4期15-22,共8页
Journal of Foshan University(Natural Science Edition)
基金
石家庄学院教学改革研究与实践项目(ZXJG-202019)。
