摘要
目的:探讨莫西沙星联合头孢哌酮钠舒巴坦钠、舒利迭对COPD并急性下呼吸道感染患者免疫球蛋白水平的影响。方法:2019年1月-2020年6月收治COPD并急性下呼吸道感染患者90例,随机分为两组,各45例。甲组使用头孢哌酮钠舒巴坦钠及舒利迭治疗;乙组使用莫西沙星联合头孢哌酮钠舒巴坦钠及舒利迭治疗。比较两组治疗效果。结果:乙组治疗6d后肺部啰音消失时间、体温正常时间、病灶消失时间及异常喘息消失时间均明显低于甲组,差异有统计学意义(P<0.05);乙组治疗6d后免疫球蛋白水平高于甲组,差异有统计学意义(P<0.05);乙组治疗6d后动脉氧分压水平高于甲组,动脉二氧化碳分压水平低于甲组,差异有统计学意义(P<0.05)。结论:使用莫西沙星联合头孢哌酮钠舒巴坦钠及舒利迭治疗COPD并急性下呼吸道感染,能够增强患者免疫力,改善患者高碳酸血症及低氧血症,有利于患者尽早康复。
Objective:To investigate the effect of moxifloxacin combined with cefoperazone sulbactam sodium and seretide on the level of immunoglobulin in patients with COPD and acute lower respiratory tract infection.Methods:From January 2019 to June 2020,90 patients with COPD and acute lower respiratory tract infection were selected,they were randomly divided into the two groups with 45 cases in each group.The group A was treated with cefoperazone sulbactam sodium and seretide.The group B was treated with moxifloxacin combined with cefoperazone sulbactam sodium and seretide.We compared the treatment effects of the two groups.Results:After 6 days of treatment,the disappearance time of pulmonary rales,recovery time of body temperature,the disappearance time of chest X-ray lesions,and the disappearance time of abnormal wheezing in the group B were significantly lower than those in the group A,the differences were statistically significant(P<0.05).The level of immunoglobulin in the group B was higher than that in the group A after 6 days of treatment,the difference was statistically significant(P<0.05).After 6 days of treatment in the group B,the level of arterial oxygen partial pressure was higher than that of the group A,the level of arterial carbon dioxide partial pressure was lower than that of the group A,the difference was statistically significant(P<0.05).Conclusion:The use of moxifloxacin combined with cefoperazone sulbactam sodium and seretide in the treatment of COPD and acute lower respiratory tract infection can enhance the patient's immunity,improve the patient's hypercapnia and hypoxemia,and help the patient recover as soon as possible.
作者
罗刚
杨爱兰
Luo Gang;Yang Ailan(Department of Respiratory Medicine,the People's Hospital of Zhijiang City,Hubei Yichang 443200)
出处
《中国社区医师》
2021年第22期29-30,共2页
Chinese Community Doctors
