摘要
子午流注学说基于"天人相应"整体观,认为人体气血随不同时辰阴阳消长而循序流注于十二经脉,与睡眠节律密切相关。胶质淋巴系统是能清除脑内代谢产物的交换流动系统,对阿尔茨海默病的进展有一定影响。通过分析子午流注学说与胶质淋巴系统防治阿尔茨海默病的研究成果,发现睡眠节律是二者影响认知功能的共同作用途径,故提出"运用子午流注学说调节睡眠节律,提高胶质淋巴系统的流动峰值,促进脑内β淀粉样蛋白代谢,进而减轻认知功能损害"的构思,以期拓展阿尔茨海默病的中医药防治思路。
Based on the holistic view of"correspondence between human beings and nature",the midnight-noon ebb-flow theory holds that qi and blood flow in the twelve meridians in sequence with the waxing and waning of yin and yang at different hours of the day,which is correlative with the circadian rhythm.Glymphatic system,a flowing exchange system,which clears intracephalic metabolites,has an effect on the progression of Alzheimer’s disease.This article analyzes the application of the midnight-noon ebb-flow theory and lymphatic system in the prevention and treatment of Alzheimer’s disease and discovers that both affect the cognitive function through the circadian rhythm.Therefore,it is argued that"the midnight-noon ebb-flow theory may be used to adjust the circadian rhythm to improve the peak flow of the lymphatic system,promote β-amyloid metabolism and alleviate cognitive disorder",which could provide reference for the prevention and treatment of Alzheimer’s disease with traditional Chinese medicine.
作者
刁华琼
丁海月
李小黎
陈琳
魏丹
张婧
李倩倩
鲁丽华
张乃文
李梦媛
Diao Huaqiong;Ding Haiyue;Li Xiaoli;Chen Lin;Wei Dan;Zhang Jing;Li Qianqian;Lu Li-hua;Zhang Naiwen;Li Mengyuan(Department of Encephalopathy,Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China;Department of Acupuncture and Moxibustion,Beijing Hospital of TCM Affiliated to Capital Medical University,Beijing 100016,China)
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2021年第6期496-499,共4页
Journal of Beijing University of Traditional Chinese Medicine
基金
国家自然科学基金面上项目(No.81673930)。
