摘要
目的:探讨毫针焠刺联合温针灸治疗风寒湿痹型膝骨关节炎的疗效及对血清IL-6、COX-2和MMP-3水平影响。方法:将本院收治的风寒湿痹型膝骨关节炎患者62例随机分为对照组(31例,温针灸疗法)和治疗组(31例,毫针焠刺联合温针灸疗法),对比两组临床疗效、VAS评分、HSS评分和WOMAC评分、中医症候积分及血清IL-6、COX-2和MMP-3水平。结果:治疗后,与对照组比较,治疗组总有效率较高,差异具有统计学意义(P<0.05);治疗后两组HSS评分明显升高,血清IL-6、COX-2和MMP-3水平、VAS评分、中医症候积分和WOMAC评分明显降低,差异具有统计学意义(P<0.05);并且治疗组改善较多(P<0.05)。结论:膝骨关节炎患者采用毫针焠刺法联合温针灸治疗具有较好的治疗效果。
Objective:To explore the therapeutic effect of filiform red-hot needling combined with needle-warming moxibustion in the treatment of knee osteoarthritis(KOA)of wind,cold and dampness Bi syndrome and to investigate its influence to the serum levels of IL-6,COX-2 and MMP-3.Methods:62 patients with KOA of wind,cold and dampness Bi syndrome were randomly divided into the control group(n=31)and the treatment group(n=31).The control group was treated with needle-warming moxibustion;on which basis,the treatment group was also treated with filiform red-hot needling.The clinical efficacy,the scores of VAS,HSS,WOMAC and TCM symptoms,as well as the serum levels of IL-6,COX-2 and MMP-3 were compared between the two groups after the treatment.Results:The total effective rate of the treatment group was significantly higher than that of the control group(P<0.05).The score of HSS was significantly increased(P<0.05),whereas the serum levels of IL-6,COX-2 and MMP-3,as well as the scores of VAS,TCM symptoms and WOMAC were significantly decreased after the treatment in the two groups(P<0.05);of which the improvements in the treatment group were more significant(P<0.05).Conclusion:Filiform red-hot needling combined with needle-warming moxibustion has better therapeutic effect in the treatment of KOA.
作者
熊雨墨
马毅
肖强兵
胡昊
李瑛
XIONG Yumo;MA Yi;XIAO Qiangbing;HU Hao;LI Ying(Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430065, China;Hubei University of Chinese Medicine, Wuhan 430065, China)
出处
《针灸临床杂志》
2021年第7期44-47,共4页
Journal of Clinical Acupuncture and Moxibustion
基金
湖北省中医院人才引进启动基金,编号:20191011。
关键词
毫针焠刺法
温针灸
风寒湿痹型
膝骨关节炎
IL-6
COX-2
MMP-3
Filiform red-hot needling
Needle-warming moxibustion
Wind,cold and dampness Bi syndrome
Knee osteoarthritis
IL-6
COX-2
MMP-3
