摘要
认知损害是癫癎患者最常见的共病之一,癫癎病程、发作频率与认知损害呈正相关,发病年龄越小认知损害越严重,癫癎发作期和发作间期癎样放电也可导致认知损害,癫癎手术治疗对认知功能影响尚不明确,迷走神经刺激术可能改善认知损害。抗癫癎药物对认知功能具有正面或负面影响。早期控制癫癎发作、抑制发作间期癎性放电、避免使用对认知功能有负面影响的药物或手术方式,有助于改善患者认知损害,提高生活质量。文中对癫癎患者认知损害及其影响因素的相关研究进展进行阐述。
Cognitive impairment is one of the most common diseases in patients with epilepsy.The course and frequency of epilepsy are positively correlated with cognitive impairment.The younger the age of onset is,the more serious the cognitive impairment is.Epileptic seizures and interictal discharges can also lead to cognitive impairment.The effect of epileptic surgery on cognitive function is not clear.Vagus nerve stimulation may improve cognitive function.Antiepileptic drugs have positive or negative effects on cognitive function.Early control of seizures,inhibition of interictal epileptic discharges and avoiding the use of drugs or surgical methods that have negative effects on cognitive function are helpful to improve patients’cognitive function and quality of life.The related research progress of cognitive function and its influencing factors in patients with epilepsy from the above aspects were expounded.
作者
徐婷
吴雪瑞
邹晓毅
XU Ting;WU Xue-rui;ZOU Xiao-yi(Department of Neurology,West China Hospital,Sichuan University,Chengdu 610041,China)
出处
《中国临床神经科学》
2021年第4期456-460,F0003,共6页
Chinese Journal of Clinical Neurosciences
基金
四川省科技计划项目(编号:2019YFS0215)。
关键词
癫癎
认知损害
影响因素
epilepsy
cognitive function
influencing factors
