摘要
目的:探讨高强度聚焦超声消融治疗子宫肌瘤患者的临床效果及对子宫内膜容受性、卵巢功能的影响。方法:选取2020年6-11月本院收治的98例子宫肌瘤患者,根据抽签法随机分为研究组和对照组,每组49例。对照组进行宫腔镜子宫肌瘤切除术,研究组进行高强度聚焦超声消融。比较治疗前后的性激素[雌激素(E2)、催乳素(PRL)、卵泡刺激素(FSH)、雄性激素(T)、黄体生成素(LH)、孕酮(P)]、子宫内膜下和子宫内膜的血流动力学指标[管化血流指数(VFI)、管化指数(VI)、血流指数(FI)]、子宫内膜容积与厚度、舒张压与收缩压。结果:治疗前,两组T、P、E_(2)、FSH、PRL、LH水平比较,差异均无统计学意义(P>0.05),治疗后,研究组T、P、E_(2)水平均低于对照组,FSH、PRL、LH水平均高于对照组,差异均有统计学意义(P<0.05)。治疗前,两组子宫内膜下和子宫内膜VEF、FI、VI比较,差异均无统计学意义(P>0.05),治疗后,研究组子宫内膜下和子宫内膜VEF、FI、VI均高于对照组,差异均有统计学意义(P<0.05)。治疗前,两组子宫内膜容积和子宫内膜厚度比较,差异均无统计学意义(P>0.05),治疗后,研究组子宫内膜容积和子宫内膜厚度均高于对照组,差异均有统计学意义(P<0.05)。治疗前,两组舒张压和收缩压比较,差异均无统计学意义(P>0.05),治疗后,研究组舒张压和收缩压均低于对照组,差异均有统计学意义(P<0.05)。结论:对子宫肌瘤患者进行高强度聚焦超声消融治疗,效果理想,可改善血流动力学指标,同时可增加内膜容积与厚度,维持舒张压与收缩压稳定,值得推广应用。
Objective:To investigate the clinical effect of high intensity focused ultrasound ablation in patients with uterine fibroids and its influence on endometrial receptivity and ovarian function.Method:A total of 98 patients with uterine fibroids in our hospital from June to November 2020 were selected,and they were randomly divided into study group and control group according to drawing of lots.The control group was treated with hysteroscopic myomectomy,and the study group was treated with high intensity focused ultrasound ablation.The sex hormones[estrogen(E2),prolactin(PRL),follicle stimulating hormone(FSH),androgen(T),luteinizing hormone(LH),progesterone(P)],under the endometrium and endometrium hemodynamic indexes[pipe flow index(VFI),tube(VI),blood flow index(FI)],volume and thickness of the film inside the uterus,diastolic blood pressure and systolic blood pressure before and after treatment were compared between two groups.Result:Before treatment,there were no significant differences in T,P,E2,FSH,PRL and LH between two groups(P>0.05),after treatment,the levels of T,P and E2 of study group were lower than those of control group,and the levels of FSH,PRL and LH were higher than those of control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in VEF,FI,VI in endometrium and under the endometrium between two groups(P>0.05),after treatment,VEF,FI,VI of under the endometrium and endometrium hemodynamic indexes of study group were higher than those of control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in endometrial volume and endometrial thickness between the two groups(P>0.05);after treatment,endometrial volume and endometrial thickness of study group were higher than those of control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant difference in diastolic blood pressure and systolic blood pressure between two groups(P>0
作者
李枫光
王瑶
徐少华
LI Fengguang;WANG Yao;XU Shaohua(Huizhou Third People’s Hospital,Huizhou 516000,China;不详)
出处
《中国医学创新》
CAS
2021年第19期155-159,共5页
Medical Innovation of China
关键词
高强度聚焦超声消融
子宫肌瘤
子宫内膜容受性
卵巢功能
High intensity focused ultrasound ablation
Uterine fibroids
Endometrial receptivity
Ovarian function
