摘要
鼻咽癌疗效评价常采用常规磁共振评价模式,单一常规磁共振只能评估肿瘤大小变化,无法对其疗效进行精准预测。功能影像技术能进一步补充疗效预测的信息,然而,单一影像学评价在肿瘤疗效评价中有一定局限性,功能影像与生物标志物联合进行疗效评价及预测,可能为鼻咽癌疗效评价模式提供新选择。文章通过对鼻咽癌疗效评价模式的现状、功能影像技术与生物标志物的单一评价模式或者联合评价模式的研究进展进行综述,为探讨精确并易于推广应用的鼻咽癌疗效评价模式提供思路。
Conventional magnetic resonance imaging(MRI)is often used to evaluate the therapeutic effect of nasopharyngeal carcinoma.Single conventional MRI can only evaluate the change of tumor size and cannot accurately predict the curative effect of tumors.Functional imaging technology can further supplement the information of curative effect prediction.However,single imaging evaluation has some limitations in the evaluation of tumor efficacy.The combination of functional imaging and biomarkers for the evaluation and prediction of curative effect may provide a new choice for the evaluation model of nasopharyngeal carcinoma.This paper reviews the progress of current status of therapeutic evaluation models for nasopharyngeal carcinoma,functional imaging technology and single or joint evaluation model of biomarkers,so as to provide ideas for the efficacy evaluation model for nasopharyngeal carcinoma which is accurate and easy to be promoted and applied.
作者
杨慧
陆颖
黄海欣
Yang Hui;Lu Ying;Huang Haixin(Department of Oncology,the Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou 545005,China)
出处
《肿瘤研究与临床》
CAS
2021年第6期464-468,共5页
Cancer Research and Clinic
基金
广西壮族自治区自然科学基金(2017GXNSFBA198005)
柳州市科技计划(2018BJ10303、2019AF10601)
柳州市科学研究与技术开发计划(2016G020203)
广西壮族自治区卫生与计划生育委员会自筹费科研课题(Z20200837、Z20170895、Z2016167)。
关键词
鼻咽肿瘤
综合疗法
功能影像技术
生物标志物
高危人群
Nasopharyngeal neoplasms
Combined modality therapy
Functional imaging
Biomarkers
Population at risk
