摘要
目的研究不同损伤情况下的骨重建行为。方法提出一种疲劳机制作用下的骨重建模型,通过建立股骨近端三维有限元模型,并结合有限元法,分别模拟3种载荷工况下的骨重建情况,分析股骨近端的力学性能及密度变化。结果通过增加载荷循环次数,使损伤不断增加。在不同损伤情况下,骨展现出不同的骨重建行为。骨重建作为一种修复机制,在一定范围内可以弥补由于疲劳损伤造成的骨量丢失。结论提出的损伤自适应重建模型可以模拟不同损伤情况下的骨重建行为,以及由于载荷循环次数过大引起的过载吸收。研究疲劳损伤作用下的骨重建行为,可以为骨折预防以及术后康复治疗提供参考。
Objective To study bone remodeling behavior under different damage conditions. Methods A bone remodeling model under fatigue mechanism was proposed. By establishing a three-dimensional( 3 D) finite element model of the proximal femur and combining with the finite element method,the bone remodeling under three loading conditions was simulated,and the mechanical properties and density changes of the proximal femur were analyzed. Results The damage increased with the number of loading cycles increasing. Under different damage conditions, bone showed different remodeling behaviors. As a kind of repair mechanism, bone remodeling could make up for the loss of bone mass due to fatigue damage within a certain range. Conclusions The damage adaptive remodeling model proposed in this study can simulate the bone remodeling behavior under different damage conditions,and the overload absorption caused by excessive loading cycles. The study on the behavior of bone remodeling under fatigue damage can provide references for fracture prevention and postoperative rehabilitation treatment.
作者
原慧
曲传咏
YUAN Hui;QU Chuanyong(School of Mechanical Engineering,Tianjin University,Tianjin 300350,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2021年第3期442-447,共6页
Journal of Medical Biomechanics
基金
国家自然科学基金项目(11972247)。
关键词
骨重建
疲劳损伤
损伤修复
近端股骨
bone remodeling
fatigue damage
damage repair
proximal femur
