摘要
目的分析重庆市某校人鼻病毒感染暴发疫情流行病学及临床特征,以期为今后此类疫情暴发处理提供参考。方法回顾性搜集2020年5—6月在学校暴发疫情呼吸道感染的患者资料,包括流行病学调查、临床表现、实验室检查、处置措施等。结果首例患者5月25日发病,末例5月31日发病,经过7 d最长潜伏期无新发患者。本次疫情为同一班68名同学中的31例发病,罹患率为45.59%(31/68),25例为住宿生,且24例居住在宿舍楼第一层;患者症状较轻,多为上呼吸道感染症状,其中咽痛26例(83.87%,26/31);发热17例(54.84%,17/31),体温最高38.1℃;咳嗽15例(48.39%,15/31),流涕14例(45.16%,14/31);31例患者实验室检测人鼻病毒核酸阳性24例,阳性率77.42%(24/31),其余实验室检查及呼吸道病毒核酸检测阴性;所有患者经过隔离对症治疗后均病情好转。结论该起疫情为重庆市首起由实验室确诊的人鼻病毒引起的普通感冒暴发疫情;本次疫情患者病情较轻,未造成更大范围的播散;加强学校学生住宿环境的消毒、患者居家隔离、注意个人卫生是防控人鼻病毒引起的上呼吸道感染疫情的关键措施。
Objective To describe the epidemiology of and clinical findings associated with a human rhinovirus(HRV)outbreak among students in a campus.Methods Relevant data(including epidemiological investigation,clinical symptoms,laboratory tests and control measures)were collected retrospectively from May to June 2020.Results The index case was identified on May 25,2020 and the last case was detected on May 31,2020.No new cases were found within a longest incubation period of 7 days.This outbreak involved 31 of 68 students in the same class,an attack rate of 45.59%(31/68).Twenty-five of the 31 students were resident students,including 24 living on the first floor of the dormitory building.The symptoms of these HRV infections were mild,mostly upper respiratory symptoms(100%),including sore throat(83.87%,26/31),fever(54.84%,17/31),cough(48.39%,15/31),and runny nose(45.16%,14/31).HRV nucleic acid test was positive in 24 cases(77.42%).The other laboratory tests,imaging findings,and respiratory virus tests did not have abnormal results.All cases improved after isolation and symptomatic treatment.Conclusions This epidemic is the first laboratory confirmed outbreak of common cold caused by HRV infection in Chongqing.Fortunately,all the cases were mild and did not result in more extensive spread.Disinfection of the living environment,isolation of cases,and personal hygiene are the key to prevention and control of the HRV outbreak.
作者
邓敏
夏晓影
杨玉霞
时志鹏
刘荷蕾
夏红
杨强
DENG Min;XIA Xiaoying;YANG Yuxia;SHI Zhipeng;LIU Helei;XIA Hong;YANG Qiang(Department of Infectious Diseases,Dazu District People’s Hospital,Chongqing 402360,China)
出处
《中国感染与化疗杂志》
CAS
CSCD
北大核心
2021年第4期418-422,共5页
Chinese Journal of Infection and Chemotherapy
基金
重庆市科卫联合医学科研项目(2019ZDXM042)。
关键词
人鼻病毒
聚集性疫情
流行病学
临床特征
学校
human rhinovirus
cluster outbreak
epidemiology
clinical characteristic
campus
