摘要
【目的】观察痛泻要方合五苓散加减治疗肝郁脾虚型腹泻型肠易激综合征(IBS-D)患者的临床疗效。【方法】采用回顾性研究方法,收集2019年6月至2020年6月期间在深圳市中医院门诊就诊的肝郁脾虚型IBS-D患者63例,按治疗方法不同分为治疗组33例和对照组30例。治疗组给予痛泻要方合五苓散加减治疗,对照组给予参苓白术散加减治疗,疗程为4周。观察2组患者治疗前后中医证候积分的变化情况,评价2组患者的临床疗效。【结果】(1)治疗4周后,治疗组的总有效率为72.7%(24/33),对照组为46.7%(14/30);组间比较,治疗组的疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的中医证候积分均较治疗前明显降低(P<0.05),且治疗组对中医证候积分的降低作用明显优于对照组,差异有统计学意义(P<0.05)。【结论】痛泻要方合五苓散加减治疗肝郁脾虚型IBS-D具有较好疗效,其疗效优于参苓白术散加减。
Objective To observe the clinical efficacy of Tongxie Yaofang(Important Formula for Relieving Diarrhea with Pain)combined with Wuling Powder for the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D)with liver stagnation and spleen deficiency type.Methods A retrospective study was conducted in 63 IBS-D patients with liver stagnation and spleen deficiency type admitted in the outpatient department of Shenzhen Traditional Chinese Medicine Hospital from June 2019 to June 2020.According to the treatment methods,the patients were divided into treatment group(33 patients)and control group(30 patients).The treatment group was treated with Tongxie Yaofang combined with Wuling Powder,and the control group was treated with Shenling Baizhu Powder,the course of treatment lasting 4 weeks.Before and after treatment,the changes of TCM syndrome scores in 2 groups were observed.And after treatment,the clinical efficacy of the two groups was evaluated.Results(1)After 4 weeks of treatment,the overall effective rate in the treatment group was 72.7%(24/33)and that in the control group was 46.7%(14/30).The intergroup comparison showed that the therapeutic effect of the treatment group was superior to that of the control group,and the difference was statistically significant(P<0.05).(2)After treatment,TCM syndrome scores in the 2 groups were significantly lower than those before treatment(P<0.05),the decrease of TCM syndrome scores in the treatment group was superior to that of the control group,and the difference was statistically significant(P<0.05).Conclusion The modified treatment with Tongxie Yaofang and Wuling Powder exerts certain efficacy for the treatment of IBS-D with liver stagnation and spleen deficiency type,and its efficacy is stronger than that of the modified treatment of Shenling Baizhu Powder.
作者
徐思思
郭绍举
XU Si-Si;GUO Shao-Ju(The Fourth Clinical Medicial School of Guangzhou University of Chinese Medicine,Shenzhen 518033 Guangdong,China;Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033 Guangdong,China)
出处
《广州中医药大学学报》
CAS
2021年第7期1346-1350,共5页
Journal of Guangzhou University of Traditional Chinese Medicine
关键词
腹泻型肠易激综合征(IBS-D)
肝郁脾虚型
痛泻要方
五苓散
参苓白术散
diarrhea-predominant irritable bowel syndrome(IBS-D)
liver stagnation and spleen deficiency type
Tongxie Yaofang
Wuling Powder
Shenling Baizhu Powder
