摘要
目的了解广西壮族自治区柳州市糖尿病(diabetes mellitus,DM)患者糖尿病视网膜病变(diabetic retinopathy,DR)的患病率及其影响因素。方法采用整群抽样的方法抽取柳州市辖区内的12个社区卫生服务中心、乡镇卫生院中确诊为DM的患者作为研究对象,对研究对象进行问卷调查、常规体检、实验室检测及眼底检查。采用非条件二分类Logistic逐步回归分析模型分析影响DM患者发生DR的危险因素。结果共调查DM患者3017例,其中有898例患者诊断为DR,占比29.8%,其中736例为轻度非增生型DR、103例为中度非增生型DR、23例为重度非增生型DR、36例为增生型DR,占比分别为82.0%、11.5%、2.5%和4.0%。二分类非条件Logistic逐步回归分析模型分析结果显示,年龄较小(OR=0.628,95%CI:0.531~0.744)、有全身疾病史(OR=0.812,95%CI:0.684~0.963)是DR的保护因素;有眼部手术史(OR=2.096,95%CI:1.632~2.693)、FPG较高(OR=1.103,95%CI:1.071~1.135)、尿白蛋白较高(OR=1.001,95%CI:1.000~1.001)、SBP较高(OR=1.011,95%CI:1.006~1.016)、心率较快(OR=1.009,95%CI:1.001~1.017)、职业为农民和自由职业(OR=1.207,95%CI:1.002~1.453)是DR的独立危险因素。结论广西壮族自治区柳州市DM患者DR患病率处于中等水平,主要以轻度非增生型DR为主。年龄、全身疾病史、眼部手术史、尿白蛋白、FPG、血压、心率、职业是DM患者发生DR的影响因素。应对DM患者加强DR的宣传教育以及筛查力度。
Objective To estimate the prevalence and related factors of diabetic retinopathy(DR)in patients with diabetes mellitus(DM)in Liuzhou,Guangxi Zhuang Autonomous Region.Methods A stratified cluster random sampling method was used to select patients who diagnosed with DM from 12 community health service centers and township health centers in Liuzhou as the research objects.Questionnaire survey,physical examination,laboratory tests and fundus examination were performed to them.Unconditional two classification Logistic stepwise regression analysis model was used to analyze the relationship between DR and various factors.Results A total of 3017 DM were included,and 898 of them presented with DR at a morbidity rate of 29.8%.Among DR patients,the number of mild,moderate,severe non-proliferative DR patients and proliferative DR patients were 736(82.0%),103(11.5%),23(2.5%)and 36(4.0%),respectively.The unconditional two classification Logistic stepwise regression analysis demonstrated,the younger people(OR=0.628,95%CI:0.531-0.744),history of systemic disease(OR=0.812,95%CI:0.684-0.963)were protective factors for DR.The history of eye surgery(OR=2.096,95%CI:1.632-2.693),higher fasting glucose(OR=1.103,95%CI:1.071-1.135),higher urinary albumin(OR=1.001,95%CI:1.000-1.001),higher systolic pressure(OR=1.011,95%CI:1.006-1.016),faster heart rate(OR=1.009,95%CI:1.001-1.017),farmer and freelance occupation(OR=1.207,95%CI:1.002-1.453)were the independent risk factors for DR occurrence.Conclusions The prevalence of DR is medium in the DM patients in Liuzhou,Guangxi Zhuang Autonomous Region,mainly with mild non-proliferative DR patients.Ages,history of systemic disease,eye surgery,urinary albumin,fasting glucose,blood pressure,heart rate and occupation are the independent risk factors for DR occurrence.The publicity and education of DR and disease screening for DM patients should be strengthened.
作者
刘金纪
王欢
龙陟罡
阳桥生
莫雄钧
黄丽
韦所苏
陈秋菊
LIU Jin-ji;WANG Huan;LONG Zhi-gang;YANG Qiao-sheng;MO Xiong-jun;HUANG Li;WEI Suo-su;CHEN Qiu-ju(Department of Ophthalmology,Liuzhou Red Cross Hospital,Liuzhou 545001,China;Prevention and Health Care Department,The People’s Hospital of Guangxi Zhuang Autonomous Region,Nanning 530000,China)
出处
《中华疾病控制杂志》
CAS
CSCD
北大核心
2021年第6期673-678,共6页
Chinese Journal of Disease Control & Prevention
基金
2019年广西医药卫生自筹经费计划课题(Z20190697)
2020年广西医药卫生自筹经费计划课题(Z20201302)。
