摘要
目的应用二维斑点追踪成像(2D-STI)技术评价正常妊娠中晚期胎儿左房时相功能。方法回顾性分析2019年1月至2020年1月在首都医科大学附属北京朝阳医院产检的正常单胎胎儿80例,采集产前24周、32周及37周胎儿心尖或心底四腔心图像,应用2D-STI获得左房储器应变及应变率(S-LAs、SR-LAs)、管道应变及应变率(S-LAe、SR-LAe)和泵应变及应变率(S-LAa、SR-LAa)。结果能够良好追踪并识别左房三个时相应变值的比例在24周、32周及37周分别为97.5%、88.8%及87.5%,三组间差异无统计学意义(P=0.051)。S-LAs在32周及37周时低于24周(均P<0.05),S-LAe在37周时高于24周及32周(均P<0.05)。S-LAa随孕周增加而减小,三组间两两比较差异有统计学意义(均P<0.05)。SR-LAs及SR-LAa在32周及37周低于24周,差异有统计学意义(均P<0.05)。SR-LAe三组间差异无统计学意义(P=0.076)。结论2D-STI技术评价胎儿左房时相功能是可行的。与孕中期相比,胎儿左房储器功能及泵功能在孕晚期减低,而管道功能在孕晚期增强,明确正常心房功能随孕周的变化可以为评估胎儿心脏发育成熟及发现胎儿心脏功能异常提供依据。
Objective To evaluate the fetal left atrial phasic function in normal pregnancy by two-dimensional speckle tracking imaging(2D-STI).Methods The antenatal examination images of 80 normal singleton fetuses from January 2019 to January 2020 in Beijing Chaoyang Hospital,Capital Medical University were retrospectively analyzed.The following parameters were acquired from apical or basal four-chamber views at 24 weeks,32 weeks and 37 weeks:global peak systolic strain and strain rate(S-LAs,SR-LAs),global conduit strain and strain rate(S-LAe,SR-LAe),global contractile strain and strain rate(S-LAa,SR-LAa).Results The possibilities to identify left atrial phasic strain at 24 weeks,32 weeks and 37 weeks were 97.5%,88.8%and 87.5%,respectively.There were no significant differences among the 3 groups(P=0.051).Compared with at 24 weeks,S-LAs was decreased at 32 weeks and 37 weeks(all P<0.05),while S-LAe at 37 weeks was higher than at 24 weeks and 32 weeks(all P<0.05).S-LAa decreased gradually among the 3 groups,and reached the lowest at 37 weeks of gestation(P<0.05).SR-LAs and SR-LAa were lower at 32 weeks and 37 weeks than at 24 weeks(all P<0.05).There was no statistical difference in SR-LAe among the three groups(P=0.076).Conclusions It is feasible to evaluate the phasic function of fetal left atrium by 2D-STI.Compared with the second trimester,the left atrial reservoir function and pump function of the fetus are decreased in the third trimester,while the ductal function is enhanced in the third trimester.The determination of the changes of normal atrial function with gestational weeks can provide a basis for the evaluation of fetal cardiac maturity and the detection of fetal cardiac dysfunction.
作者
叶晓光
李一丹
蔡绮哲
孙兰兰
朱维维
吕秀章
Ye Xiaoguang;Li Yidan;Cai Qizhe;Sun Lanlan;Zhu Weiwei;Lyu Xiuzhang(Department of Echocardiography,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2021年第6期489-493,共5页
Chinese Journal of Ultrasonography
基金
北京朝阳医院1351人才培养计划(CYMY-2017-28)。
关键词
超声心动描记术
胎儿
心房功能
左
二维斑点追踪成像
Echocardiography
Fetus
Atrial function,left
Two-dimensional speckle tracking imaging
