摘要
Four new sesquiterpenoids,artemyrianins A-D(1-4),and three new norlignans,artemyrianins E-G(5-7),together with five known compounds(8-12),were isolated from the aerial parts of Artemisia myriantha(Asteraceae).The new compounds were established by spectroscopic data analyses(HRMS,IR,1D and 2D NMR),and their absolute configurations were confirmed by the single-crystal X-ray diffraction or ECD calculations.The isolates showed cytotoxicity against HepG2 cells with IC50 values ranging from 33.3 to 145.2μM.
基金
supported by the Yunnan Wanren Project(YNWR-KJLJ-2019-002)
the Program of Yunling Scholarship,the Reserve Talents of Young and Middle-aged Academic and Technical Leaders in Yunnan Province,and the Youth Innovation Promotion Association,CAS(2013252).