摘要
目的观察大剂量左氧氟沙星联合前列腺按摩对ⅢA型前列腺炎患者症状及生活质量的影响。方法选取2016年5月-2019年7月辽宁省朝阳县中心医院收治的ⅢA型前列腺炎患者94例,采用随机数字表法分为观察组和对照组,每组47例。对照组给予前列腺按摩治疗,观察组在对照组的基础上联合大剂量左氧氟沙星治疗。比较2组患者的临床疗效、治疗前后前列腺炎症状评分、白细胞计数、生活质量评分及尿动力学指标[残余尿量(VRU)和最大尿流率(MFR)]。结果观察组治疗总有效率为93.62%,高于对照组的72.34%(χ^(2)=7.532,P=0.006)。治疗后,2组患者NIH-CPSI评分、前列腺炎症状评分、白细胞计数及VRU均低于治疗前,生活质量评分及MFR高于治疗前,且观察组变化幅度大于对照组(P<0.05)。结论大剂量左氧氟沙星联合前列腺按摩治疗ⅢA型前列腺炎的效果较好,可显著减轻患者的症状,改善患者的生活质量,值得临床推广应用。
Objective To observe the effect of high dose levofloxacin combined with prostate massage on symptoms and quality of life of patients with typeⅢA prostatitis.Methods A total of 94 patients withⅢA prostatitis admitted to Chaoyang County People’s Hospital in Liaoning Province from May 2016 to July 2019 were selected.Using random number table method,they were divided into observation group and control group,with 47 cases in each group.The control group was given prostate massage therapy,and the observation group was treated with high dose levofloxacin on the basis of the control group.The clinical efficacy,prostatitis symptom score,white blood cell count,quality of life score and urodynamic indicators[residual urine volume(VRU)and maximum urinary flow rate(MFR)]were compared between the two groups of patients before and after treatment.Results The total effective rate of treatment in the observation group was 93.62%,which was higher than 72.34%in the control group(χ^(2)=7.532,P=0.006).After treatment,the NIH-CPSI score,prostatitis symptom score,white blood cell count,and VRU of the two groups were lower than before treatment,and the quality of life score and MFR were higher than before treatment,and the observation group changed more than the control group(P<0.05).Conclusion High dose levofloxacin combined with prostate massage is effective in treatingⅢA prostatitis,which can significantly reduce the symptoms of patients and improve the quality of life of patients.It is worthy of clinical application.
作者
李想
LI Xiang(Chaoyang County People's Hospital,Liaoning Province,Chaoyang City 122000,China)
出处
《临床合理用药杂志》
2021年第20期21-23,26,共4页
Chinese Journal of Clinical Rational Drug Use
