摘要
目的对2016-2018年云南省疟疾病例个案和疫点调查处置情况进行综合分析,评估消除疟疾策略和措施的实施效果,为下一步消除疟疾和防止输入疟疾再传播工作提供科学依据。方法对2016-2018年云南省疟疾病例个案和疫点调查处理报告进行提取、录入、整理,分析其中的病例、媒介监测和控制等数据,使用Microsoft Excel 2016进行数据录入、整理和初步分析;使用SPSS 20.0软件对数据进行统计分析,对不同感染来源地的虫种构成进行卡方检验。使用ArcGIS 10.0软件进行疫点媒介监测结果空间分布绘图。结果2016-2018年云南省16个州、市报告了951例疟疾病例,其中以间日疟为主(85.70%,815例),本地病例和复发病例各1例,其余均为境外输入病例,输入病例中缅甸占85.28%(811例),非洲和东南亚输入的疟原虫种构成进行卡方检验,显示非洲和东南亚输入云南省疟疾病例虫种构成比存在统计学差异(χ^(2)=477.240,P<0.001),其中非洲以恶性疟为主,东南亚则以间日疟为主,输入病例高峰期为4~7月份,在12月份存在一个小高峰;全省疫点处置共捕获4种传疟媒介,中华按蚊对0.15%高效氯氰菊酯校正死亡率为79.30%;0.05%溴氰菊酯的校正死亡率为57.87%,显示这两种杀虫剂在云南已经产生了抗性。结论中缅边境地区防止输入疟疾再传播仍然是云南省接下来一段时间还将面临的重大挑战,在春节等节假日期间必须加强对境外疟疾输入病例的发现、追踪和管理,在重点地区开展常用杀虫剂的敏感性监测,科学指导开展媒介控制。
This study sought to extract,input,and sort malaria cases for an investigation and processing report in Yunnan Province from 2016 to 2018.The data on cases,vector monitoring,and control were analyzed,and Microsoft Excel 2016 was used for data entry,sorting,and preliminary analysis.SPSS 20.0 software was used for statistical analysis of the data,and chi square tests were used to assess the compositions of different infection sources.The spatial distribution of vector monitoring results was mapped with ArcGIS 10.0 software.Comprehensive analysis of malaria cases and the reactive response investigation and treatment in 2016-2018 in Yunnan Province was performed to evaluate the effects of implementation of malaria elimination strategies and measures,thus providing a scientific basis for the next steps in malaria elimination and prevention of retransmission of imported malaria.From 2016 to 2018,951 malaria cases were reported in 16 prefectures and cities of Yunnan Province,of which the main malaria cases were vivax malaria(85.70%,815);there was one local case and one recurrent case.The remainder were imported cases.Myanmar accounted for 85.28%(811 cases)of the imported cases.Chi square tests were used to assess the composition of imported Plasmodium species from Africa and Southeast Asia,χ^(2)=477.240,P<0.001.The results indicated a significant difference in the proportion of malaria cases imported from Africa and Southeast Asia to Yunnan Province,in which falciparum malaria was dominant in Africa,and vivax malaria was dominant in Southeast Asia.The peak of imported cases was from April to July.Four malaria vectors were captured in the entire province.The corrected mortality rate of Anopheles sinensis to 0.15%beta cypermethrin was 79.30%,and that to 0.05%deltamethrin was 57.87%,thus indicating that resistance to the two insecticides has developed in Yunnan.In summary,the prevention of retransmission of imported malaria in the border area between China and Myanmar will remain a major challenge for Yunnan Province in t
作者
林祖锐
张豪
孙晓东
丁春丽
赵晓涛
吕全
魏春
周耀武
LIN Zu-rui;ZHANG Hao;SUN Xiao-dong;DING Chun-li;ZHAO Xiao-tao;LYU Quan;WEI Chun;ZHOU Yao-wu(Yunnan Institute of Parasitic Diseases,Yunnan Provincial Center of Malaria Research,Yunnan Provincial Key Laboratory of Vector-borne Diseases Control and Research,Yunnan Institute of Parasitic Diseases Innovative Team of Key Techniques for Vector Borne Disease Control and Prevention(Developing),Training Base of International Scientific Exchange and Education in Tropical Diseases for South and Southeast Asia,Pu’er 665000,China;Lijiang Center for Disease Control and Prevention,Lijiang 674100,China)
出处
《中国人兽共患病学报》
CAS
CSCD
北大核心
2021年第6期525-531,共7页
Chinese Journal of Zoonoses
基金
国家自然科学基金项目(No.81960374)。
关键词
疟疾个案
调查处置
云南省
malaria cases
investigation and disposal
Yunnan Province
