摘要
目的:对每QALY支付意愿(Willingness to Pay per QALY,WTP/QALY)的实证研究进行系统评价,为我国今后开展此类研究提供参考。方法:检索PubMed、Embase和HTA Database数据库,搜集公开发表的每QALY支付意愿的实证研究。结果:最终纳入36项研究,测量QALY的最常用方法是视觉模拟量表,其次是EQ-5D;测量WTP的最常用方法是开放式问题,其次是投标博弈。37.14%的研究报告单一阈值,62.86%的研究报告阈值区间。分析阈值与人均GDP的比值发现,对于单一阈值研究,82.97%的比值小于2;对于阈值区间研究,78.05%的比值区间的上限值小于2。结论:应加强国内对每QALY支付意愿的实证研究,不推荐使用WHO推荐的阈值。
Objective:To evaluate the empirical research on willingness to pay per QALY systematically,so as to provide a reference for future research in China.Methods:PubMed,Embase and HTA Database were searched to collect empirical research on the willingness to pay per QALY.Results:36 researches were finally included.The most commonly used method to obtain QALY was the visual analog scale,followed by EQ-5D.The most commonly used method to obtain WTP was open-ended question,followed by bidding game.37.14% of the studies reported a single threshold and 62.86% of them reported a threshold interval.By analyzing the ratio of QALY to per capita GDP,it was found that for the single threshold studies,82.97% of them had a ratio less than 2.For the threshold interval studies,the upper limit of the ratio interval in 78.05% of them was less than 2.Conclusion:Empirical research on willingness to pay per QALY in China should be strengthened.It is not recommended to use the threshold recommended by WHO.
作者
李环
李程洪
刘红海
黄梅香
张治国
LI Huan(School of Medicine and Health Management,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei,430030,China)
出处
《医学与社会》
北大核心
2021年第7期36-41,共6页
Medicine and Society
基金
中央高校基本科研业务费专项资金资助项目,编号为2019WKYXZX009
国家自然科学基金资助项目,编号为71273100。
关键词
质量调整生命年
成本效果阈值
支付意愿
Quality-Adjusted Life Year
Cost Effectiveness Threshold
Willingness to Pay
