摘要
工业微生物及其产品广泛用于工业、农业、医药等诸多领域,相关产业在国民经济中具有举足轻重的地位。高效的菌株是提高生产效率的核心,而先进发酵技术和仪器平台对充分开发菌株代谢潜能也很重要。近年来,工业微生物领域的研究取得了快速进展,人工智能、高效基因组编辑技术和合成生物学技术逐渐广泛使用,相关产业应用也在不断扩展。为进一步促进工业微生物在生物制造等领域的应用,《生物工程学报》特组织出版专刊,从微生物菌株的多样性和生理代谢、菌株改造技术、发酵过程优化和放大,高通量微液滴培养装备开发以及工业微生物应用等方面,分别阐述目前的研究进展,并展望未来的发展趋势,为促进工业微生物及生物制造等产业的发展奠定基础。
Industrial microorganisms and their products are widely used in various fields such as industry,agriculture,and medicine,which play a pivotal role in economy.Efficient industrial strains are the key to improve production efficiency,and advanced fermentation technology as well as instrument platform is also important to develop microbial metabolic potential.In recent years,rapid development has been achieved in research of industrial microorganisms.Artificial intelligence,efficient genome-editing and synthetic biology technologies have been increasingly applied,and related industrial applications are being accomplished.In order to promote utilization of industrial microorganisms in biological manufacturing,we organized this special issue on innovation and breakthrough of industrial microorganisms.Progress including microbial strain diversity and metabolism,strain development technology,fermentation process optimization and scale-up,high-throughput droplet culture system,and applications of industrial microorganisms is summarized in this special issue,and prospects on future studies are proposed.
作者
邓禹
赵心清
Yu Deng;Xin-Qing Zhao(National Engineering Laboratory for Cereal Fermentation Technology,Jiangnan University,Wuxi 214122,Jiangsu,China;State Key Laboratory of Microbial Metabolism,Joint International Research Laboratory of Metabolic&Developmental Sciences,School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,Shanghai 200240,China)
出处
《生物工程学报》
CAS
CSCD
北大核心
2021年第3期801-805,共5页
Chinese Journal of Biotechnology
关键词
工业微生物
基因组编辑
代谢工程
合成生物学
发酵优化和放大
高通量培养装备
industrial microorganisms
genome editing
metabolic engineering
synthetic biology
fermentation optimization and scale-up
high-throughput culture system
