摘要
目的探讨小剂量阿司匹林联合低分子肝素治疗妊娠期高血压的效果。方法68例妊娠期高血压患者随机分为两组各34例,对照组采用低分子肝素治疗,观察组采用低分子肝素联合小剂量阿司匹林治疗,比较两组的临床疗效、终止妊娠孕周、新生儿体质量及不良妊娠结局。结果观察组的总有效率为97.06%,显著高于对照组的76.47%(P<0.05)。观察组的终止妊娠孕周及新生儿体质量均显著优于对照组(P<0.05)。观察组的不良妊娠结局发生率为5.88%,显著低于对照组的26.47%(P<0.05)。结论小剂量阿司匹林联合低分子肝素治疗妊娠期高血压的效果显著,可有效延长孕周,增加新生儿体质量,改善不良妊娠结局。
Objective To explore the effect of low-dose aspirin combined with low molecular weight heparin in the treatment of gestational hypertension.Methods 68 patients with gestational hypertension were randomly divided into two groups,with 34 cases in each group.The control group was treated with low molecular weight heparin,and the observation group was treated with low molecular weight heparin combined with low-dose aspirin.The clinical efficacy,gestational age at termination of pregnancy,neonatal weight and adverse pregnancy outcomes were compared between two groups.Results The total effective rate of observation group was 97.06%,significantly higher than 76.47%of control group(P<0.05).The gestational age at termination of pregnancy and neonatal weight of observation group were significantly better than those of control group(P<0.05).The incidence of adverse pregnancy outcomes of observation group was 5.88%,significantly lower than 26.47%of control group(P<0.05).Conclusions Low-dose aspirin combined with low molecular weight heparin in the treatment of gestational hypertension has significant effect,which can effectively prolong the gestational age,increase neonatal weight,and improve the adverse pregnancy outcome.
作者
马伟杰
MA Weijie(Department of Obstetrics and Gynecology,Changge Maternal and Child Healthcare Hospital,Changge 461500,China)
出处
《临床医学工程》
2021年第6期767-768,共2页
Clinical Medicine & Engineering
关键词
妊娠期高血压
小剂量阿司匹林
低分子肝素
Gestational hypertension
Low-dose aspirin
Low molecular weight heparin