摘要
目的了解揭阳地区乳腺癌的发病情况和诊疗现状,掌握揭阳地区乳腺癌的流行病学特征。方法回顾性分析广东省揭阳市人民医院659例经病理确诊的原发性乳腺癌患者的临床资料。结果659例乳腺癌患者诊断时中位年龄52岁(四分位数46,60岁);除1例男性患者外,其余均为女性。52.7%(347/658)女性患者为绝经后乳腺癌;浸润性导管癌所占比例最大,为83.1%(548/659);Ⅰ、Ⅱ期乳腺癌比率为62.2%(410/659);Luminal B(HER2+)所占比例最大,为27.3%(180/659),所占比例最小的是三阴性,为11.2%(74/659);进行新辅助化疗、辅助化疗患者比例分别为23.8%(157/659)、50.8%(335/659),手术方式以改良根治术为主,占比55.7%(367/659),其次是保乳术占19.9%(131/659),单纯乳腺切除术+前哨淋巴结活检18.2%(120/659)。结论揭阳地区乳腺癌患者诊断年龄偏大,呈单峰分布,绝经后女性患者偏多,病理类型以浸润性导管癌为主,Ⅳ期患者比例有逐年上升趋势,手术治疗方式以改良根治术为主,保乳术和单纯乳腺切除术+前哨淋巴结活检应用率高,表明该地区患者对美观和功能有较高要求。
Objective To investigate the epidemiological characteristics and current management of breast cancer in Jieyang city.Methods Clinical data of patients who were histologically diagnosed with primary breast cancer between January 2015 and December 2019 in our hospital were retrospectively analyzed.Results A total of 659 patients with median age of 52 years(interquartile interval:46-60)with breast cancer were enrolled.Except for one male patient,the other patients were female;and 52.7%(347/658)of these female patients were diagnosed with postmenopausal breast cancer.Invasive ductal carcinoma was the most common histological type(83.1%,548/659).The proportion of breast cancer in Stage Ⅰ and Ⅱ was 62.2%(410/659).Luminal B(HER2+)accounted for 27.3%(180/659)of the total patients,while triple negative(11.2%,74/659)was the least common.As for the treatment,23.8%(157/659)and 50.8%(335/659)of patients received neoadjuvant chemotherapy and adjuvant chemotherapy,respectively.Modified radical resection was the primary surgical method(55.7%,367/659),followed by breast-conserving surgery(19.9%,131/659),and simple mastectomy and sentinel lymph node biopsy(18.2%,120/659).Conclusion In summary,patients with breast cancer in Jieyang city are relatively old,with age showing unimodal distribution,and more than half patients were postmenopausal women.The primary pathological type is invasive ductal carcinoma.Of note,the proportion of patients with Stage Ⅳ tends to increase year by year.Modified radical resection remains the main surgical treatment,and breast-conserving surgery and simple mastectomy are also preferred,indicating patients in this region have higher demand for aesthetics and function.
作者
蔡振海
杨朝蓉
黄伟斌
黄佳旭
CAI Zhen-hai;YANG Zhao-rong;HUANG Wei-bin;HUANG Jia-xu(Breast Surgery of Jieyang People′s Hospital,Jieyang 522000,Guangdong,China;不详)
出处
《广东医学》
CAS
2021年第6期701-705,共5页
Guangdong Medical Journal
关键词
乳腺癌
流行病学特征
回顾性研究
揭阳地区
breast cancer
epidemiological characteristics
retrospective study
Jieyang
