摘要
目的探究跌打祛风膏贴敷联合温经活血方熏洗对糖尿病痛性神经病变病人疗效观察。方法选取2016年6月至2018年4月佛山市中医院收治的94例糖尿病痛性神经病变病人,其中47例给予口服甲钴胺、西洛他唑和阿米替林进行治疗作为对照组,47例给予跌打祛风膏贴敷联合温经活血方熏洗治疗作为研究组,观察两组病人的疗效、中医证候积分、现存疼痛强度(PPI)评分及神经传导速度情况。结果治疗后,研究组总有效率87.23%(41/47),高于对照组70.21%(33/47)(P<0.05);两组病人中医证候积分[(6.85±1.54)分、(4.65±1.06)分]、PPI评分[(2.95±0.67)m/s、(2.33±0.52)m/s]较治疗前下降[(7.76±1.77)分、(7.81±1.79)分、(4.12±0.94)m/s、(4.11±0.93)m/s](P<0.05),研究组低于对照组(P<0.05);胫神经运动神经传导速度(MNCV)、感觉神经传导速度(SNCV)和腓总神经MNCV、SNCV水平均较治疗前增高(P<0.05),研究组高于对照组(P<0.05)。结论跌打祛风膏贴敷联合温经活血方熏洗对糖尿病痛性神经病变病人有较好的治疗效果,可有效降低疼痛、提高神经传导速度,且副作用较少,值得推广。
ObjectiveTo explore the therapeutic effect of Dieda Qufeng plaster combined with Wenjing Huoxue prescription fumiga-tion on diabetic painful neuropathy.MethodsA total of 94 patients with diabetic painful neuropathy admitted to Foshan Hospital of TCM from June 2016 to April 2018 were selected.Among them, 47 patients treated with oral mecobalamin, cilostazole and amitriptylinewere selected as control group, and 47 patients treated with Dieda Qufeng ointment application combined with Wenjing Huoxue pre-scription fumigation and washing were selected as study group. The curative effect, TCM syndrome score, present pain index(PPI)score and nerve conduction velocity of the two groups were observed.ResultsAfter treatment, the total effective rate was 87.23%(41/47) in the study group, which was significantly higher than 70.21%(33/47) in the control group(P < 0.05). The scores of TCM syn-dromes [(6.85±1.54) score,(4.65±1.06) score] and PPI [(2.95±0.67) m/s,(2.33±0.52) m/s] in the two groups were lower than those be-fore treatment [(7.76±1.77) score,(7.81±1.79) score,(4.12±0.94) m/s,(4.11±0.93) m/s](P < 0.05), while those in the study group werelower than those in the control group(P < 0.05). The levels of motor nerve conduction velocity(MNCV), sensory nerve conduction veloc-ity(SNCV) in tibial nerve and common peroneal nerve were higher than those before treatment(P < 0.05), and those in the study groupwere higher than those in the control group(P < 0.05).ConclusionsDieda Qufeng Ointment application combined with Wenjing Huoxue prescription fumigation and washing has a better therapeutic effect on diabetic painful neuropathy. It can effectively reduce pain andimprove nerve conduction velocity, and has fewer side effects, which is worthy of promoting.
作者
陈苹
魏爱生
王甫能
劳美玲
吕丽雪
CHEN Ping;WEI Aisheng;WANG Funeng;LAO Meiling;LYU Lixue(Foshan Traditional Chinese Medicine Hospital,Foshan,Guangdong 528000,China)
出处
《安徽医药》
CAS
2021年第7期1455-1458,共4页
Anhui Medical and Pharmaceutical Journal
基金
2010年广东省中医药局科研项目(2010003)。
关键词
糖尿病神经病变
经皮贴片
浴疗学
跌打祛风膏
温经活血方
Diabetic neuropathies
Transdermal patch
Balneology
Dieda Qufeng ointment
Wenjing Huoxue prescription
