摘要
腹膜透析(peritoneal dialysis,PD)是终末期肾脏病患者的有效肾脏替代治疗方式,PD相关并发症是限制PD进行的重要原因。白细胞介素-6(interleukin-6,IL-6)在PD相关并发症的多种病理生理过程中起重要作用。本文主要综述IL-6在腹膜透析相关性腹膜炎(peritoneal dialysis-associated peritonitis,PDAP)、腹膜纤维化、心血管事件等PD常见并发症中研究进展,归纳总结IL-6与PD相关并发症之间的联系。
Peritoneal dialysis(PD)is an effective renal replacement therapy for patients with end-stage renal disease and peritoneal dialysis-related complications have restrict the development of PD.Interleukin-6 plays an important role in pathophysiological processes of peritoneal dialysis-related complications.This review summarized the latest researches of IL-6 in peritoneal dialysis-associated peritonitis,peritoneal fibrosis and cardiovascular events and elucidated the relationship between IL-6 and peritoneal dialysis-related complications.
作者
杨凡
包宇实
Yang Fan;Bao Yu-shi(Department of Nephrology,First Affiliated Hospital,Harbin Medical University,Harbin 150000,China)
出处
《临床肾脏病杂志》
2021年第6期512-515,共4页
Journal Of Clinical Nephrology
基金
黑龙江省卫生健康委科研课题(2019-017)。
关键词
白细胞介素-6
腹膜透析相关性腹膜炎
腹膜纤维化
免疫炎症
上皮-间充质转化
Interleukin-6
Peritoneal dialysis-associated peritonitis
Peritoneal fibrosis
Immune inflammatory
Epithelial-to-mesenchymal transition
