摘要
目的:探讨肾性骨病患者中医证候及证型分布特点,为中医临床治疗本病提供数据支持。方法:收集100例肾性骨病患者的临床资料,根据《中药新药临床指导原则》以及中国中医药出版社出版的《中医内科学》中肾病、骨痹病设计相应的中医证候问卷,收集患者的主要临床症状及四诊资料,累计积分聚类分析,最后总结出肾性骨病患者的主要中医证候。结果:经过对100例肾性骨病患者聚类分析,发现频数最多的十项症状依次为:下肢骨痛,腰膝酸软,畏寒怕冷,皮肤瘙痒,倦怠乏力、下肢为甚,面色晦暗、爪甲干枯,纳呆,口干舌红,大便干燥,胸闷心悸。进一步聚类分析后发现本病以肝肾阴虚、肾阳虚衰证和瘀血内阻证为主。结论:在肾性骨病患者中,多以肝肾不足为主要表现,部分患者合并瘀血内阻的情况,因此治疗本病应重在滋补肝肾,同时勿忘活血化瘀。
Objective:To investigate the distribution characteristics of TCM syndromes and syndrome types in patients with renal bone disease,and to provide data support for TCM clinical treatment of the disease.Methods:100 patients with renal bone disease was lollected.TCM syndrome questionnaires were designed.The main clinical symptoms and four-diagnosis data of the patients were collected.Finally,the main TCM syndromes of patients were summarized.Results:After clustering analysis of 100 patients with renal bone disease,the ten most frequent symptoms were found in order:bone pain in lower limbs,soreness of waist and knees,chills and fear of cold,skin itching,fatigue and more obvious weakness of low limbs,dull complexion and dry nails,anorexia,dry mouth,dry stools,chest tightness and palpitations.After further cluster analysis,it is found that the disease is mainly composed of liver and kidney,Yang-deficiency(阳虚)of kidney and blood stasis internal resistance.Conclusion:In patients with nephropathy and bone disease,the main manifestation is liver and kidney deficiency,and some patients have internal resistance of blood stasis.Therefore,the treatment of this disease should focus on nourishing the liver and kidney,while not forgetting to promote blood circulation and remove blood stasis.
出处
《中医临床研究》
2021年第10期55-57,共3页
Clinical Journal Of Chinese Medicine
基金
海阳市科技计划项目(2016054)。
关键词
肾性骨病
辨证分型
聚类分析
Renal bone disease
Syndrome differentiation
Cluster analysis
