摘要
目的分析慢性阻塞性肺疾病急性加重(Acute exacerbation of chronic obstructive pulmonary disease,AECOPD)康复临床研究的文献特征和现状,为AECOPD康复研究及应用提供参考。方法检索中国知网、Pubmed等数据库的AECOPD康复临床研究文献,检索时间为建库至2019年12月1日,提取合格文献的相关信息并建立数据库,对纳入文献的基本特征、内容特征进行统计分析。结果(1)纳入文献246篇,包括期刊文献224篇91.06%、学位论文16篇6.50%、会议论文6篇2.44%。(2)224篇期刊文献分布在148种期刊上,其中中文核心期刊43种(56,22.76%),SCI期刊25种(35,14.23%)。(3)干预措施主要包括4类:西医康复(167,69.29%)、中医康复(35,14.52%)、中西医结合康复(10,4.15%)和其他(5,2.07%);干预时机多为急性加重住院期间(229,95.02%);干预周期多为出院前(70,29.05%),其次为12周(30,12.45%)和2周(26,10.79%)。(4)纳入的RCT整体方法学质量偏低;未发现与AECOPD康复干预有关的严重不良事件。结论目前AECOPD康复研究日益增多,高质量证据有待进一步加强,获益的结论尚需多中心、大样本的临床试验验证。
Objective To analyze the literature characteristics and development status of clinical research on AECOPD rehabilitation to provide a reference for the rehabilitation research and application of AECOPD.Methods AECOPD rehabilitation clinical researches were retrieved from CNKI,PubMed and other databases,and the retrieval time was from the establishment of the database to December 1,2019.Relevant information of qualified literature was extracted and a database was established,and the basic characteristics and content characteristics of the included literature were statistically analyzed.Results(1)In total,246 papers(168 in Chinese and 78 in English)were included,including 224 journal papers(91.06%),16 degree papers(6.50%),and 6 conference papers(2.44%).(2)In total,224 journal papers were distributed in 148 journals,of which 43 were Chinese Core Journals(56,22.76%),25 were SCI journals(35,14.23%).(3)Intervention measures mainly included 4 categories:Western medicine rehabilitation(167,69.29%),traditional Chinese medicine rehabilitation(35,14.52%),integrated traditional Chinese and Western medicine rehabilitation(10,4.15%)and others(5,2.07%);the intervention time was mostly during acute exacerbation of hospitalization(229,95.02%);most of the intervention cycle was before discharge(70,29.05%),followed by 12 weeks(30,12.45%)and 2 weeks(26,10.79%).(4)The overall methodological quality of the included RCTs was average,and no serious adverse events related to AECOPD rehabilitation intervention had been identified.Conclusion At present,AECOPD rehabilitation is increasing,and high-quality evidence needs to be further strengthened.The conclusion still needs to be verified by multi-center,large-sample clinical trials.
作者
张东
张海龙
王露
郭雯
李宣霖
李建生
Zhang Dong;Zhang Hailong;Wang Lu;Guo Wen;Li XuanLin;Li Jiansheng(Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan&Education Ministry of P.R.China,Henan Key Laboratory of Chinese Medicine for Respiratory Disease,Henan University of Chinese Medicine,Zhengzhou 450046,China;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450003,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2021年第3期892-898,共7页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
河南省中医管理局河南省中医药科学研究专项重点课题(2018JDZX007):慢性阻塞性肺疾病急性加重早期介入呼吸导引操干预的临床疗效评价研究,负责人:张海龙
国家自然科学基金委员会面上项目(81973781):方证对应治疗AECOPD痰热壅肺证患者的生物效应机制与肠道菌群研究,负责人:张海龙。
关键词
慢性阻塞性肺疾病
急性加重
康复
文献分析
Chronic of obstructive pulmonary disease
Acute exacerbations
Rehabilitation
Literature analysis