摘要
[目的]观察运用相同的舒喘方药治疗慢性阻塞性肺疾病(COPD)稳定期和支气管哮喘持续期两类不同的疾病,能否实现异病同治及异病同治法的临床疗效。[方法]5家研究中心纳入276例COPD稳定期和支气管哮喘持续期患者,作为"异病";将276例患者采用分层随机分组方法分为试验组和对照组,试验组采用舒喘方药加西医常规治疗作为干预措施,对照组采用中药安慰剂加西医常规治疗作为干预措施;将相同的论治方法作为"同治"。疗程为4周。[结果]试验组和对照组比较,显效率分别为:COPD稳定期12.68%、2.82%;哮喘持续期18.46%、4.62%;有效率分别为:COPD稳定期52.11%、29.58%;哮喘持续期56.92%、29.23%。试验组疗效明显优于对照组,疗效有统计学差异(P<0.05)。试验组COPD稳定期与支气管哮喘持续期疗效间比较无统计学差异(P>0.05)。[结论]采用异病同治法治疗COPD稳定期和支气管哮喘持续期可获得较为满意的疗效,并且两种不同的疾病在一定时期可采取相同的治疗原则进行辨证论治。
[Objective ] To observe and apply same Shuchuans Decoction on chronic obstructive puhnonary disease （COPD） in stable and bronchitis asthma continua] periods, if it can get the clinical effects of same treatment for different diseases. [Method] Take 276 cases as ＂different diaseses＂, and randomly divide them into test group and control group, the test one takes Shuchuang Decoction and routine western medicine; other one, TCM placebo with western medicine, the latter was for intervening measure, both for 4w. [Result] By comparison of both, the marked effective rates were： COPD in stable period, 12.68% and 2.82% ;asthma continual period, 18.46% and 4.62%;the effective rates were：COPD in stable period,52, l l% and 29.58%;asthma continual period, 56.92% and 29.23%. The test group was much better than control one, with cure effect of statistical meaning. In test group, the two periods had no statistical difference. [Conclusion] The said method has good cure effect on COPD in stable period and bronchitis asthma continual period, and both diseases can take same treatment principle in some period by differentiation of signs.
出处
《浙江中医药大学学报》
CAS
2012年第8期874-879,共6页
Journal of Zhejiang Chinese Medical University
基金
国家中医药管理局中医药行业科研专项项目(7-21)~~
关键词
COPD稳定期
支气管哮喘持续期
异病同治
疗效分析
COPD in stationary phase
bronchitis asthma Continuous period
same treatment to different diseases
Curative effect analysis
