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破格救心汤联合针刺治疗慢性肺源性心脏病临床研究 被引量:4

Clinical Study of Using Poge Jiuxin Decoction Combined with Acupuncture in the Treatment of Chronic Pulmonary Heart Disease
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摘要 目的:探讨破格救心汤联合针刺治疗慢性肺源性心脏病(CPHD)疗效。方法:选取2018年1月~2019年10月本院156例CPHD患者,随机数字表法分为A、B、C三组,每组各52例患者,C组给予常规西医治疗,B组在常规西医干预的基础上应用针刺治疗,A组在常规西医干预的基础上使用破格救心汤联合针刺治疗,比较三组症状积分、心功能、肺功能、血液流变学指标及不良反应。结果:A组治疗有效率94.23%高于B组80.77%,B组高于C组63.46%(P<0.05);A组治疗后咯痰、咳嗽、哮鸣音、喘息、紫绀、自汗畏风、气短乏力、舌质症状积分均低于B组,B组低于C组(P<0.05);A组治疗后舒张末期容积(EDV)、收缩末期容积(ESV)水平低于B组与C组,左室射血分数(LVEF)水平高于B组与C组(P<0.05);A组治疗后第1秒用力呼气容积占用力肺活量的百分比(FEV1/FVC%)、最高呼气流速(PEF)、最大通气量(MVV)水平高于B组,B组高于C组(P<0.05);A组治疗后血浆粘度、全血高切粘度、全血低切粘度、红细胞压积低于B组,B组低于C组(P<0.05);三组患者不良反应发生率比较(P>0.05)。结论:破格救心汤联合针刺治疗可有效改善CPHD患者临床症状,提高患者心肺功能,改善血液流变学指标,疗效显著,安全性较高。 Objective: To explore the curative effect of using Poge Jiuxin Decoction combined with acupuncture in the treatment of chronic pulmonary heart disease(CPHD). Methods: A total of 156 CPHD patients in the hospital from January 2018 to October 2019 were enrolled and divided into groups A, B and C by random number table method, 52 cases in each group. The group C was treated with routine western medicine, the group B was given acupuncture on basis of routine western medicine, and the group A was given Poge Jiuxin Decoction and acupuncture on the basis of routine western medicine. The scores of clinical symptoms, cardiac function, pulmonary function and hemorheology indexes, and adverse reactions were compared among the three groups. Results: The response rate of clinical treatment was the highest in the group A, followed by the group B and the group C(94.23%, 80.77%, 63.46%)(P < 0.05). After treatment, scores of symptoms(cough, expectoration, wheezing, wheezing rale, cyanosis, shortness of breath, fatigue, spontaneous perspiration and anemophobia, tongue body) were the highest in the group C, followed by the group B and the group A(P < 0.05). After treatment, levels of end-diastolic volume(EDV) and end-systolic volume(ESV) in the group A were lower than those in the group B and the group C, while the level of left ventricular ejection fraction(LVEF) was higher than that in the group B and the group C(P < 0.05). After treatment, forced expiratory volume in 1 second/forced vital capacity(FEV1/FVC%), peak expiratory flow(PEF) and maximal voluntary ventilation(MVV) were the highest in the group A, followed by the group B and the group C(P < 0.05). After treatment, plasma viscosity, whole blood high-shear viscosity, whole blood low-shear viscosity and hematokrit were the highest in the group C, followed by the group B and the group A(P < 0.05). There was no significant difference in the incidence of adverse reactions among the three groups(P > 0.05). Conclusion: Poge Jiuxin Decoction combined with acupuncture can effectiv
作者 李春霞 LI Chunxia(Department of Respiratory and Critical Care Medicine,Tongnan District People's Hospital of Chongqing City,Chongqing 402660,China)
出处 《四川中医》 2021年第5期69-73,共5页 Journal of Sichuan of Traditional Chinese Medicine
关键词 慢性肺源性心脏病 针刺 破格救心汤 临床研究 Chronic pulmonary heart disease Acupuncture Poge Jiuxin Decoction Clinical research
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