摘要
目的分析原发性闭角型青光眼(PACG)患者术后继发恶性青光眼的影响因素。方法回顾性分析2015年5月至2020年5月在本院行手术治疗的76例PACG患者的临床资料,根据术后复查是否继发恶性青光眼将其分为继发组(n=14)和非继发组(n=62)。比较两组的眼部检查相关参数,采用单因素和Logistic回归分析法探讨PACG患者术后继发恶性青光眼的影响因素。结果继发组术前眼压、前房深度均大于非继发组,晶体厚度和眼轴长度均小于非继发组(P<0.05)。单因素分析结果显示,年龄、病程、青光眼类型、房角结构、术前眼压、晶体厚度、眼轴长度、前房深度均是影响PACG患者术后继发恶性青光眼的可能危险因素(P<0.05)。Logistic回归分析结果表明,年龄、房角结构、眼轴长度均是影响PACG患者术后继发恶性青光眼的独立危险因素,术前眼压是其保护因素(P<0.05)。结论年龄较小、房角完全关闭和眼轴长度较短是影响PACG患者术后继发恶性青光眼的危险因素,术前较低的眼压水平是其保护因素。因此针对PAGG患者的上述相关因子提前做出干预,有助于降低术后继发恶性青光眼的发生率,对促进患者术后恢复和改善预后有积极的临床意义。
Objective To analyze the influencing factors of postoperative malignant glaucoma in patients with primary angle-closure glaucoma(PACG).Methods The clinical data of 76 patients with PACG who underwent surgery in our hospital from May 2015 to May 2020 were retrospectively analyzed.The patients were divided into secondary group(n=14)and non-secondary group(n=62)according to whether the patients had secondary malignant glaucoma after surgery.The ocular examination related parameters of the two groups were compared,and the influencing factors of postoperative secondary malignant glaucoma in PACG patients were investigated by univariate analysis and Logistic regression analysis.Results Preoperative intraocular pressure and anterior chamber depth in the secondary group were greater than those in the non-secondary group,and the lens thickness and axial length were smaller than those in the non-secondary group(P<0.05).Univariate analysis result showed that age,course of disease,glaucoma type,atrial Angle structure,preoperative intraocular pressure,lens thickness,axial length and anterior chamber depth were the possible risk factors for postoperative secondary malignant glaucoma in PACG patients(P<0.05).Logistic regression analysis result showed that age,atrial Angle structure and axial length were independent risk factors for postoperative secondary malignant glaucoma in PACG patients,and preoperative intraocular pressure was its protective factor(P<0.05).Conclusion Young age,complete closure of atrial Angle and short axial length are risk factors for postoperative secondary malignant glaucoma in PACG patients,and the lower intraocular pressure levels before surgery is its protective factor.Therefore,early intervention targeting above related factors in PAGG patients is helpful to reduce the incidence of secondary malignant glaucoma after surgery,and has positive clinical significance in promoting postoperative recovery and improving prognosis of patients.
作者
党江波
李钢锋
DANG Jiangbo;LI Gangfeng(Ophthalmology Department,Yulin Hospital of Traditional Chinese Medicine,Yulin 719000;Ophthalmology Department,Yangling Demonstration Zone Hospital,Xianyang 712100,China)
出处
《临床医学研究与实践》
2021年第18期32-34,共3页
Clinical Research and Practice
