摘要
目的探究3~6岁儿童支气管哮喘的临床特征及影响因素。方法选取2019年2月~2020年9月期间我院收治的3~6岁急性发作期儿童支气管哮喘150例及同期3~6岁健康体检儿童150例作为研究对象,分别作为病例组(n=150)及对照组(n=150),收集全部入院儿童的临床资料,总结临床特征,采用logistic回归分析剖析3~6岁儿童支气管哮喘的影响因素。结果病情严重程度:轻度为70例,中度为48例,重度为32例。logistic回归分析结果表明,哮喘家族史、粉尘、食物过敏、湿疹、过敏性鼻炎、被动吸烟、宠物、装修、花粉接触史、维生素D缺乏、近期呼吸道感染、Ig E升高、IL-17A升高是儿童支气管哮喘的危险独立因素,母乳喂养是儿童支气管哮喘的保护因素,(P<0.05)。结论儿童支气管哮喘主要症状是上呼吸道感染,其影响因素众多,哮喘家族史、粉尘、食物过敏、湿疹、Ig E升高、IL-17A升高等因素,是儿童支气管哮喘的危险独立因素,母乳喂养是保护因素,临床上主要注意控制危险因素。
Objective To explore the clinical characteristics and influencing factors of bronchial asthma in children aged 3~6 years old.Methods 150 children aged 3~6 years old with acute onset bronchial asthma and150 children aged 3~6 years who came for physical examination during the same period from February 2019 to September 2020 were selected respectively as the case group(n=150)and the control group(n=150).The clinical data of all hospitalized children were collected,their clinical characteristics were summarized,and the influencing factors of bronchial asthma in children aged 3~6 years old were analyzed by Logistic regression analysis.Results Severity of the disease:70 cases were mild,48 cases were moderate and 32 cases were severe.Logistic regression analysis results showed that family history of asthma,dust,food allergies,eczema,allergic rhinitis,passive smoking,pets,decorate,pollen exposure history,lack of vitamin D,respiratory infections,Ig E recent rise and IL-17 A increase were child bronchial asthma risk independent factors,and breast-feeding was children bronchial asthma protection factor(P<0.05).Conclusion The main symptom of childhood bronchial asthma is upper respiratory tract infection,and its influencing factors are numerous.Family history of asthma,dust,food allergy,eczema,elevated IG E,elevated IL-17 A and other factors are independent risk factors for children bronchial asthma.Breastfeeding is a protective factor,and clinical attention should be paid to the control of risk factors.
作者
谢翠翠
刘志钟
刘威
XIE Cui-cui;LIU Zhi-zhong;LIU Wei(Department of Pediatrics,Mingguang People′s Hospital,Chuzhou,Anhui 239400,China;Department of Pediatrics,the First Affiliated Hospital of China University of Science and Technology,Hefei,Anhui 230036,China)
出处
《临床肺科杂志》
2021年第7期1026-1029,共4页
Journal of Clinical Pulmonary Medicine
关键词
3~6岁
儿童支气管哮喘
临床特征
影响因素
3~6 years old
bronchial asthma in children
clinical features
influencing factors
