摘要
The incidence of allergic disease has increased rapidly in recent decades in both developed and developing countries.[1]In China,pollen of Artemisia is one of the most important outdoor allergen as reported by the first national pollen survey across all provinces.[2]Artemisia pollen has been found to be an important cause of seasonal asthma.[3]Artemisia vulgaris and Artemisia annua are the most important Artemisia species in China.A.vulgaris mainly grows in western regions,while A.annua is abundant in the densely populated northern and eastern regions.[4]Immunoglobulin E(IgE)antibodies play a key role in allergy diseases.They are synthesized and released by B cells and bind to high-affinity IgE receptors on mast cells or basophils.[5]Once the patients are exposed to corresponding allergens,the effector cells will be triggered and then release its mediator,leading to an allergic inflammation.
基金
supported by grants from the National Natural Science Foundation of China(Nos.81871265,81771725,U1832212,and 81971515)。
