摘要
鼻咽癌(NPC)是我国南方及东南亚地区最常见的恶性肿瘤之一,其发病率和病死率均居头颈恶性肿瘤之首。联合铂类的同步放化疗是NPC标准治疗模式,但临床上发现部分NPC患者出现放疗抵抗,预后极其不良。所以急需进行对NPC放疗抵抗的研究,以降低NPC放疗抗性,增加其放疗敏感性,改善患者预后。该文对近年来国内外NPC放疗抵抗的相关研究予以综述。
Nasopharyngeal carcinoma(NPC)is one of the most common malignant tumors in south China and southeast Asia.Its prevalence rate and mortality rate rank the first of head and neck malignant tumors.The concurrent chemoradiotherapy combined with platinum is the standard treatment mode for NPC.However,some patients with NPC have been found to be resistant to radiotherapy and have a very poor prognosis.Therefore,it is urgent to study the radiotherapy resistance of NPC,so as to reduce the radiotherapy resistance of NPC,increase its radiotherapy sensitivity and improve the prognosis of the patients.This paper reviews the researches at home and abroad on radiotherapy resistance of NPC in recent years.
作者
龚秋月(综述)
骆文龙(审校)
GONG Qiuyue;LUO Wenlong(Department of Otolaryngology,Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)
出处
《重庆医学》
CAS
2021年第11期1958-1961,共4页
Chongqing medicine
基金
重庆市科技局基金项目(cstc2018jscx-msybX0361,cstc2018jscx-mszdX0040)。
关键词
鼻咽肿瘤
放疗抵抗
放疗敏感性
综述
nasopharyngeal carcinoma
radiotherapy resistance
radiotherapy sensitivity
progress
