摘要
目的观察耳穴贴压联合左旋多巴治疗学龄前儿童弱视的临床疗效。方法纳入弱视儿童143例,随机分为观察组(72例,121眼)和对照组(71例,106眼)。两组均予戴镜、遮盖和针对训练,观察组予耳穴贴压联合口服左旋多巴治疗,对照组仅口服左旋多巴。治疗3个月后比较两组临床疗效、视功能、视觉敏感度和不良反应发生情况。结果治疗后,观察组基本痊愈率和总有效率均高于对照组,差异均有统计学意义(P<0.05)。观察组治疗后矫正辐辏范围和矫正分开范围均大于对照组(P<0.05),且矫正近立体视锐度小于对照组(P<0.05)。两组治疗后各个空间频率下的对比度均较治疗前明显提高(P<0.05),且观察组治疗后均显著高于对照组(P<0.05)。观察组不良反应发生率低于对照组,两组比较差异具有统计学意义(P<0.05)。结论耳穴贴压联合口服左旋多巴治疗学龄前儿童弱视的临床疗效优于单一口服左旋多巴治疗,提高其视功能和视觉敏感度,并减少不良反应的发生。
Objective To investigate the clinical efficacy of auricular plaster therapy plus levodopa for amblyopia in preschool children.Methods One hundred and forty-three amblyopic children were enrolled and randomized to an observation group(72 cases,121 eyes)and a control group(71 cases,106 eyes).Both groups were given glasses,covering and targeted training.The observation group received auricular plaster therapy plus oral administration of levodopa and the control group,oral administration of levodopa alone.The clinical therapeutic effects,visual functions,visual acuities and adverse reactions were compared between the two groups after three months of treatment.Results After treatment,the basic cure rate and the total efficacy rate were higher in the observation group than in the control group with statistically significant differences(P<0.05).The corrected convergence range and the corrected separation range were larger and the corrected near-stereoscopic acuity was lower in the observation group than in the control group(P<0.05).After treatment,the contrast at each spatial frequency increased significantly in the two groups compared with before(P<0.05)and was significantly stronger in the observation group than in the control group(P<0.05).The incidence of adverse reactions was lower in the observation group than in the control group with a statistically significant difference(P<0.05).Conclusions Auricular plaster therapy plus oral administration of levodopa is clinically more effective than oral administration of levodopa alone in treating amblyopia in preschool children.It can improve their visual function and visual sensitivity and reduce the occurrence of adverse reactions.
作者
陈垂海
李元朝
CHEN Chui-hai;LI Yuan-chao(Shenzhen Bao’an Hospital of Traditional Chinese Medicine,Guangdong,Shenzhen 518133,China)
出处
《上海针灸杂志》
2021年第6期751-755,共5页
Shanghai Journal of Acupuncture and Moxibustion
关键词
耳穴贴压
弱视
儿童
学龄前
左旋多巴
视功能
视觉敏感度
Auricular plaster therapy
Amblyopia
Children,Preschool
Levodopa
Visual function
Visual acuity