摘要
目的分析尿毒症患者内瘘失功的影响因素。方法选取2012年6月至2016年1月在我院行动静脉内瘘(AVF)手术并于门诊长期血液透析的143例尿毒症患者作为研究对象,根据内瘘术后3年内是否发生内瘘失功将患者分为通畅组(101例)和失功组(42例)。比较两组的一般资料,并分析影响尿毒症患者内瘘失功的相关因素。结果两组的年龄、糖尿病肾病、术后红外线照射、术后抗血小板聚集、手术方式、血磷、PTH水平比较,差异具有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,性别、年龄、糖尿病肾病、术后抗血小板聚集、手术方式、吸烟、血磷水平是尿毒症患者内瘘失功的独立影响因素(P<0.05)。结论性别、年龄、糖尿病肾病、术后抗血小板聚集、手术方式、吸烟、血磷水平是尿毒症患者内瘘失功的独立影响因素;采用改良端侧吻合方式、术后抗血小板聚集、戒烟可以降低内瘘失功发生率,延长内瘘使用寿命。
Objective To analyze the influencing factors of internal fistula dysfunction in uremic patients.Methods A total of 143 uremia patients who underwent arteriovenous fistula(AVF)operation and had long-term hemodialysis in our hospital from June 2012 to January 2016 were selected as the study objects.According to whether internal fistula dysfunction occurred within 3 years after operation,the patients were divided into patency group(101 cases)and dysfunctional group(42 cases).The general data of the two groups were compared,and the related factors affecting the internal fistula dysfunction of uremia patients were analyzed.Results There were significant differences in age,diabetic nephropathy,postoperative infrared irradiation,postoperative anti-platelet aggregation,operation method,blood phosphorus and PTH levels between the two groups(P<0.05).The multivariate Logistic regression analysis showed that gender,age,diabetic nephropathy,postoperative antiplatelet aggregation,operation method,smoking and blood phosphorus level were the independent influencing factors of the internal fistula dysfunction of uremia patients(P<0.05).Conclusion Gender,age,diabetic nephropathy,postoperative antiplatelet aggregation,operation method,smoking and blood phosphorus level were the independent influencing factors of the internal fistula dysfunction of uremia patients.Improved end-to-side anastomosis,anti-platelet aggregation and smoking cessation can reduce the incidence of internal fistula failure and prolong the life of fistula.
作者
于兆军
姜斌
YU Zhaojun;JIANG Bin(Feicheng Hospital Affiliated to Shandong First Medical University,Feicheng 271600,China)
出处
《临床医学研究与实践》
2021年第16期53-54,73,共3页
Clinical Research and Practice
关键词
血液透析
动静脉内瘘
内瘘失功
改良吻合方式
尿毒症
hemodialysis
arteriovenous fistula
internal fistula dysfunction
improved anastomosis
uremia
