摘要
目的对首发精神分裂症患者进行药物治疗的治疗效果进行分析,探究药物疗效。方法69例首发精神分裂症患者,随机分为A组、B组、C组,各23例。A组患者使用阿立哌唑治疗,B组患者采用利培酮治疗,C组患者采用氯丙嗪治疗。对比三组认知功能、冷执行能力。结果治疗后,患者的延迟视觉记忆、即刻视觉记忆、延迟逻辑评分均为A组>B组>C组,差异有统计学意义(P<0.05)。连线测试A、连线测试B、河内塔测试的反应时间A组<B组<C组,连线测试A、连线测试B的错误个数A组<B组<C组,河内塔测试的操作步骤A组<B组<C组,差异均有统计学意义(P<0.05)。结论对于首发精神分裂症患者采用阿立哌唑治疗可以有效改善其精神分裂的症状,使患者的冷执行能力得到改善,而且药物治疗的安全性较高,不会对患者造成不良影响。
Objective To analyze the therapeutic effect of different antipsychotics on cognitive function of patients with first-episode schizophrenics and explore the drug efficacy.Methods A total of 69 patients with first-episode schizophrenics were randomly divided into group A, group B and group C, with 23 cases in eachgroup. Group A was treated with aripiprazole, group B was treated with risperidone, and group C was treated withchlorpromazine. The cognitive function and cold execution ability of the three groups were compared. ResultsAfter treatment, the patients’ delayed visual memory, immediate visual memory, and delayed logic scores weregroup A > group B > group C, and the difference was statistically significant (P<0.05). The reaction time ofconnection test A, connection test B, Hanoi tower test was group A < group B < group C, the number of errors ofconnection test A, connection test B were group A < group B < group C, and the operation steps of Hanoi towertest were group A < group B < group C. All the difference was statistically significant (P<0.05). ConclusionAripiprazole can effectively improve the symptoms of schizophrenia in patients with first-episode schizophrenics,improve the cold executive ability of patients, and the safety of drug treatment is high, which will not cause adverseeffects on patients.
作者
杨宏亮
YANG Hong-liang(Department of Psychiatry,Shenyang Mental Health Center,Shenyang 110168,China)
出处
《中国实用医药》
2021年第15期113-115,共3页
China Practical Medicine
关键词
抗精神病药物
首发精神分裂症
认知功能
Antipsychotics
First-episode schizophrenics
Cognitive function
