摘要
息肉状脉络膜血管病变(polypoidal choroidal vasculopathy,PCV)是一种常见于亚洲人群的视网膜疾病,眼底镜下表现为橘红色结节性病变,可合并有浆液性或血性视网膜色素上皮层脱离及视网膜下出血。吲哚菁绿血管造影(indocyanine green angiography,ICGA)检查是其临床诊断金标准,OCT及OCTA等技术的兴起提供了PCV诊断的新思路,OCT能清晰地分层显示异常分支血管网(branching vascular network,BVN)所在层面,且因其无创性及便捷性为随访带来极大便利,临床也针对PCV的OCT特征制定了诊断标准。PCV治疗包括激光治疗、光动力疗法(photodynamic therapy,PDT)、抗VEGF、玻璃体切除术及联合治疗方案,其中以抗VEGF或联合PDT治疗应用较为广泛。为规范PCV诊疗,本文对其临床特征、诊断及治疗进展进行综述。
Polypoid choroidal angiopathy(PCV)is a common fundus disease in Asian people.It presented as orange-red nodular lesions under ophthalmoscope,which can associate with serous or bloody retinal pigment epithelial detachment and subretinal hemorrhage.Indocyanine green angiography(ICGA)is still recognized as the gold standard for diagnosis,but the rise of new auxiliary examination technologies such as OCT and OCTA also provide us with new ideas for the diagnosis of PCV.OCT can clearly display the level of branching vascular network(BVN),and brings us great convenience for follow-up because of its non-invasive and convenience.Clinical diagnosis criteria have also been established according to the OCT features of PCV.With the deepening of understanding of the PCV,different treatment options have been proposed,including monotherapy(such as,thermal laser photocoagulation,intravitreal anti-vascular endothelial growth factor,photodynamic therapy and vitrectomy)and combination therapy.In order to standardize the diagnosis and treatment of PCV,clinical features,diagnosis and treatment progress of PCV were reviewed in this paper.(Int Rev Ophthalmol,2021,45:103-110)
作者
陈丽娜
徐国兴
Chen Lina;Xu Guoxing(Fujian Institute of Ophthalmology,Department of Ophthalmology,the First Affiliated Hospital of Fujian Medical University,Fuzhou 350005,China)
出处
《国际眼科纵览》
2021年第2期103-110,共8页
International Review of Ophthalmology
基金
国家自然科学基金(81770948)
福建省科技创新领军人才基金(2016B011)。
