摘要
目的:了解不同加工食品对ACE活性的影响,为筛选具有降血压作用的食品提供数据支撑。方法:选择15种饮料、5种坚果及8种其它固体加工食品进行水提取、乙醇提取和胃蛋白酶解,采用高效液相色谱法(HPLC)检测马尿酸含量变化,了解提取物对体外血管紧张素转化酶(ACE)活性的影响。结果:绝大多数食品的乙醇提取物能促进ACE活性,而水提取和酶解产物大多数抑制ACE活性。含牛奶的饮料有显著的ACE抑制作用,其它饮料对ACE的抑制作用较弱。开心果水提物显著促进ACE活性。核桃和火腿肠的酶解产物具有显著的ACE抑制作用,核桃的胃蛋白酶提取液稀释10倍后,显著抑制ACE活性,具有较好的降血压效果。结论:一些加工食品对血压有影响,同种食品中升降血压的物质并存。食用含牛奶的饮料或核桃,可能有利于减缓高血压。
Objective:To investigate the effect of different processed foods on ACE activity,so as to provide data support for screening for foods with antihypertensive effect.Methods:The experiments of water extraction,pepsin hydrolysate and ethanol extraction of 15 kinds of drinks,5 kinds of nuts and other 8 kinds of processed foods was carried out.The hippuric acid content was detected by high performance liquid chromatography(HPLC),and their effects on angiotensin converting enzymes(ACE)activity in vitro were determined.Result:Most of ethanol extracts from 5 kinds of nuts and other processed foods promoted ACE activity,but most of their water extracts or pepsin hydrolysate inhibited ACE activity.The beverages containing milk had significant ACE inhibitory activity,while other beverages only weakly affected ACE activity.The pistachio water extract significantly promoted ACE activity.The pepsin hydrolysate of walnut and ham sausage significantly inhibited ACE activity,and the ACE activity was still significantly inhibited after the pepsin hydrolysate of walnut diluted 10 times.Some processed foods might affect blood pressure.In most foods,substances that raise and lower blood pressure may co-exist in the same food.Consumption of milk or walnuts may help to reduce high blood pressure.
作者
王柯诺
从俊峰
顾双
王向阳
Wang Kenuo;Cong Junfeng;Gu Shuang;Wang Xiangyang(College of Food Science and Biotechnology Engineering,Zhejiang Gongshang University,Hangzhou 310018)
出处
《中国食品学报》
EI
CAS
CSCD
北大核心
2021年第5期90-95,共6页
Journal of Chinese Institute Of Food Science and Technology
基金
浙江省公益技术研究计划农业项目(LGN18C 200014)
浙江省一流学科开放基金项目(2017SIAR204)。
关键词
加工食品
血管紧张素转化酶
高血压
processed food
angiotensin converting enzymes
hypertension
