摘要
目的探讨妊娠期糖尿病并发高脂血症的危险因素及其相关营养管理措施。方法选取2019年1月至2020年5月在廊坊市某医院产科建立产前健康档案并能按正常产前检查要求进行产检的妊娠期糖尿病孕妇作为研究对象进行血脂水平检测,并对妊娠期糖尿病并发高血脂症孕妇进行8周的营养管理,采用描述流行病学分析方法对妊娠期糖尿病孕妇发生高血脂症影响因素进行分析,并对营养管理前后血糖和血脂指标进行比较。结果本研究共对782例妊娠期糖尿病孕妇进行研究,年龄20~42岁,平均年龄(28.41±6.32)岁,孕周24~28周,平均(26.14±1.25)周。其中有139例(17.77%)妊娠期糖尿病孕妇发生高脂血症。多因素Logistic回归分析显示,年龄≥35岁(OR=2.280),孕前BMI≥24(OR=2.004)、畜肉摄入过量(OR=2.073)是妊娠期糖尿病孕妇并发高脂血症的危险因素。经营养管理干预后,妊娠期糖尿病并发高脂血症孕妇的TG、TC、LDL-C均比干预前低,HDL-C均比干预前高(P<0.05)。结论年龄≥35岁、孕前超重/肥胖、畜肉摄入过量是孕妇发生妊娠期糖尿病并发高脂血症的危险因素,应根据个体情况进行营养管理,对妊娠期糖尿病并发高脂血症患者的血糖和血脂水平进行更有效的控制,改善妊娠结局。
Objective To investigate the risk factors of gestational diabetes mellitus(GDM)complicated with hyperlipidemia and their related nutritional management measures.Methods From January 2019 to May 2020,pregnant women with GDM who have established prenatal health records in the obstetrics department of a hospital in Langfang City and can carry out prenatal examination according to the requirements of normal prenatal examination were selected as the research objects for blood lipid level detection,and nutritional management was carried out for GDM pregnant women complicated with hyperlipidemia for 8 weeks. Descriptive epidemiological analysis was used to analyze the influencing factors of hyperlipidemia in GDM pregnant women,and the blood glucose and blood lipid indexes before and after nutrition management were compared.Results A total of 782 pregnant women with GDM aged 20-42 years old were investigated in this study,with an average age of(28.41 ± 6.32)years. The gestational age was 24-28 weeks,with an average of(26.14 ±1.25)weeks.Among them,139(17.77%)cases had hyperlipidemia.Multivariate Logistic regression analysis showed that age ≥35 years old(OR=2.280),pre-pregnancy BMI ≥24(OR=2.004),excessive meat intake(OR=2.073)were the risk factors of hyperlipidemia in pregnant women with GDM.After the intervention of nutritional management,GDM pregnant women complicated with hyperlipidemia had lower TG,TC and LDL-C than that before the intervention,and higher HDL-C than thatbefore the intervention(P< 0.05).Conclusion The risk factors of GDM complicated with hyperlipidemia are age ≥ 35 years old,overweight/obesity before pregnancy and excessive meat intake.Nutritional management should be tailored on an individual basis to achieve more effective control of blood glucose and lipid levels and improve pregnancy outcomes in GDM pregnant women complicated with hyperlipidemia.
作者
韩晔
张前
任阳
李丹
王亚娟
蒋漫红
刘丽花
HAN Ye;ZHANG Qian;REN Yang;LI Dan;WANG Ya-juan;JIANG Man-hong;LIU Li-hua(Petro China Central Hospital of Hebei,Langfang 065000,China)
出处
《华南预防医学》
2021年第4期461-464,共4页
South China Journal of Preventive Medicine
基金
河北省廊坊市科技支撑计划项目(2018013161)。
关键词
妊娠期糖尿病
高脂血症
营养管理
影响因素
Gestational diabetes mellitus
Hyperlipidemia
Nutritional management
Influencing factor