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运用“以通为用”的络病理论治疗糖尿病下肢血管病变临床研究 被引量:11

Clinical Study on the Treatment of Lower Extremity Vascular Diseases of Diabetes by Using the Collateral Disease Theory
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摘要 目的观察"以通为用"的络病理论指导下应用中药配合针刺处方治疗糖尿病下肢血管病变的临床疗效。方法选取本科室糖尿病下肢血管病变患者60例,应用随机数字表法平均分为治疗组和对照组各30例。对照组、治疗组均给予前列地尔注射液静脉注射的基础治疗,治疗组额外给予中药汤剂(当归、白芍、桂枝、细辛、生姜、大枣、桃仁、红花、川芎、地龙)配合针刺(大钟、公孙、丰隆、飞扬、气海、关元、肾俞、命门、三阴交、太溪、复溜、足三里)治疗。疗效评价指标为中医证候评分、西医临床症状评分、踝肱指数、下肢动脉内径及峰值流速。结果中医证候评分:治疗组治疗后主症、次症、总分较对照组治疗后均下降且差异有统计学意义(P<0.05);西医临床症状评分:治疗组治疗后较对照组治疗后评分上升且差异有统计学意义(P<0.05),对照组显效率:60%,治疗组显效率:83%;踝肱指数:治疗组较对照组治疗后踝肱指数增高且差异有统计学意义(P<0.05);治疗后治疗组的股动脉、腘动脉、足背动脉的血管内径及峰流速较对照组明显改善且差异有统计学意义(P<0.05)。结论应用"以通为用"的络病理论制定的中药配合针刺的处方治疗糖尿病下肢血管病变能够取得显著的临床疗效。 Objective To observe the clinical efficacy of Chinese medicine combined with acupuncture prescription in the treatment of diabetic lower extremity vascular diseases under the guidance of the theory of collaterals disease. Methods 60 patients with diabetic lower extremity vascular disease in our department were randomly divided into treatment group and control group by random number table method. Control group,treatment group were given the basis of the front row,injection intravenous treatment,treatment group was given extra herbal medicinal broth([Danggui(Angelicae Sinensis Radix),Baishao(Paeoniae Radix Alba),Guizhi(Cinnamomi Ramulus),Xixin(Asari Radix Et Rhizoma),Shengjiang(Zingiberis Rhizoma Recens),Dazao(Jujubae Fructus),Taoren(Persicae Semen),Honghua(Carthami Flos),Chuanxiong(Chuanxiong Rhizoma),Dilong(Pheretima)] with acupuncture [Dazhong(KI4),Gongsun(SP4),Fenglong(ST40),Feiyang(BL58),Qihai(RN6),Guanyuan(RN4),Shenshu(BL23),Mingmen(DU4),Sanyinjiao(SP6),Taixi(KI3),Fuliu(KI7),Zusanli(ST36)]treatment. The indexes of efficacy evaluation were TCM syndrome score,Western medicine clinical symptom score,ankle brachial index,lower limb artery diameter and peak flow rate. Results TCM syndrome score:after treatment,the main symptoms,secondary symptoms and total scores of the treatment group were significantly lower than those of the control group(P<0.05). Clinical symptom score of Western medicine:after treatment,the score of the treatment group increased significantly compared with that of the control group(P<0.05),with significant efficiency of 60% in the control group and 83% in the treatment group. Ankle brachial index:there was significant difference between the treatment group and the control group in the increase of ankle brachial index after treatment(P<0.05). After treatment,the vessel diameter and peak velocity of femoral artery,popliteal artery and dorsal foot artery in the treatment group were significantly improved compared with those in the control group(P<0.05). Conclusion The prescription of Chinese med
作者 杜鹃 李长辉 崔聪 朱凌云 DU Juan;LI Changhui;CUI Cong;ZHU Lingyun(Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)
出处 《辽宁中医药大学学报》 CAS 2021年第3期147-150,共4页 Journal of Liaoning University of Traditional Chinese Medicine
基金 辽宁省中医药临床学(专)科能力建设项目(2018-125) 辽宁省科学计划项目面上项目(2015020390)。
关键词 糖尿病下肢血管病变 络病 踝肱指数 “脉络—血管系统病”理论 diabetic lower limb vascular disease collateral disease ankle-brachial index theory of"venus-vascular system disease"
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