摘要
目的:观察任脉区段药物铺灸联合低频经皮穴位电刺激(TEAS)治疗少弱精子症的临床疗效。方法:将105例少弱精子症患者随机分为联合组、低频组和药物组,每组35例。药物组采用口服维生素E软胶囊、辅酶Q10胶囊、五子衍宗丸治疗;低频组取肾俞、脾俞进行TEAS治疗(2 Hz,10~15 mA),隔日1次,每次30 min;联合组在低频组的基础上,予以任脉区段(神阙至中极)药物铺灸治疗,每10天治疗1次。均治疗3个月。观察各组患者治疗前及治疗2、3个月后的精液常规(浓度、正常形态率、精子活力)、精浆超氧化物歧化酶(SOD)和丙二醛(MDA)含量及中医证候积分,并评定临床疗效。结果:(1)与治疗前比较,除药物组治疗2个月后精子形态指标外,3组患者治疗2、3个月后精液常规各项指标均改善(P<0.01);联合组治疗2、3个月后精液常规各项指标均优于药物组和低频组(P<0.01)。(2)与治疗前比较,3组患者治疗2、3个月后精浆SOD含量升高、MDA含量降低(P<0.01),且变化幅度联合组均大于其他两组(P<0.01)。(3)与治疗前比较,联合组治疗2、3个月后及药物组、低频组治疗3个月后中医证候积分降低(P<0.01);治疗2、3个月后,联合组中医证候积分低于药物组和低频组(P<0.01)。(4)联合组、药物组、低频组总有效率分别为85.7%(30/35)、68.6%(24/35)、65.7%(23/35),联合组临床疗效优于药物组和低频组(P<0.05)。结论:任脉区段药物铺灸联合低频TEAS治疗可改善少弱精子症患者的精液常规,降低精子氧化应激损伤,临床疗效优于药物和TEAS治疗。
Objective To observe the clinical effect of herb-separated moxibustion on segmental conception vessel combined with low-frequency transcutaneous electrical acupoint stimulation(TEAS) for asthenospermia and oligospermia. Methods A total of 105 patients with asthenospermia and oligospermia were randomly divided into a combination group, a TEAS group and a medication group, 35 cases in each one. In the medication group, vitamin E capsules, coenzyme Q10 capsules,Wuzi Yanzong pills were taken. In the TEAS group, TEAS was applied at Shenshu(BL 23) and Pishu(BL 20), 2 Hz in frequency, 10-15 mA in intensity, once every 2 days, 30 min each time.On the base of the treatment as the TEAS group, herb-separated moxibustion on segmental conception vessel [Shenque(CV 8) to Zhongji(CV 3)] was applied in the combination group, once every 10 days. A total of 3 months were required in the 3 groups.Before treatment and 2, 3 months into treatment, the semen routine indexes(concentration, normal morphology rate, sperm motility), seminal plasma contents of superoxide dismutase(SOD) and malondialdehyde(MDA) and TCM syndrome score were observed in the 3 groups, and the clinical efficacy was evaluated. Results Compared before treatment, except for the sperm morphology 2 months into treatment in the medication group, the semen routine indexes 2, 3 months into treatment were improved in the 3 groups(P<0.01), and the semen routine indexes 2, 3 months into treatment in the combination group were superior to the medication group and the TEAS group(P<0.01). Compared before treatment, the seminal plasma contents of SOD were increased and MDA were decreased 2, 3 months into treatment in the 3 groups(P<0.01), and the changes of the combination group were larger than the medication group and the TEAS group(P<0.01). Compared before treatment, the TCM syndrome scores 2, 3 months into treatment in the combination group, and 3 months into treatment in the medication group and the TEAS group were decreased(P<0.01). The TCM syndrome scores 2, 3 months int
作者
房连强
李星凌
袁双双
张奇文
韩德雄
FANG Lian-qiang;LI Xing-ling;YUAN Shuang-shuang;ZHANG Qi-wen;HAN De-xiong(Department of Acupuncture and Moxibustion,Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310012,China;Department of Rehabilitation,Shenzhen Futian District Hospital of TCM)
出处
《中国针灸》
CAS
CSCD
北大核心
2021年第5期515-520,共6页
Chinese Acupuncture & Moxibustion
基金
浙江省中医药科学研究基金项目:2019ZB063。
关键词
少弱精子症
任脉区段
铺灸
经皮穴位电刺激(TEAS)
asthenospermia and oligospermia
segmental conception vessel
herb-separated moxibustion
transcutaneous electrical acupoint stimulation(TEAS)
