摘要
急性胰腺炎是临床常见急腹症之一,以胰腺局部炎症反应为主要特征,伴或不伴有其他器官功能改变。肠道菌群失衡与炎症反应的激活是急性胰腺炎发病的两大危险因素。文章对近年来肠道菌群与白细胞介素6(IL-6)/糖蛋白130(gp130)炎症信号通路在急性胰腺炎发病机制中的研究进展进行综述。
Acute pancreatitis is one of the most common acute abdominal diseases.It is characterized by local inflammation of the pancreas with or without changes in the function of other organs.Dysbacteriosis and activation of inflammatory response are risk factors for acute pancreatitis.This review focuses on recent advances in the study of intestinal microbiota and interleukin-6(IL-6)/glycoprotein 130(gp130)inflammatory signaling pathway in the pathogenesis of acute pancreatitis.
作者
肖樱艳
崔艳
李艳
XIAO Yingyan;CUI Yan;LI Yan(Laboratory Medicine Center,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China)
出处
《检验医学》
CAS
2021年第5期565-568,共4页
Laboratory Medicine
关键词
肠道菌群
炎症
白细胞介素6
糖蛋白130
急性胰腺炎
Intestinal microbiota
Inflammation
Interleukin-6
Glycoprotein 130
Acute pancreatitis
