摘要
目的:探讨全凭静脉麻醉对腹股沟疝手术患者血流动力学与免疫功能的影响。方法:选取2018年6月-2020年5月在本院进行腹股沟疝修补术的94例患者,根据随机信封抽签原则把患者分为观察组与对照组,各47例。对照组给予静吸复合麻醉,观察组给予全凭静脉麻醉。比较两组不同时间点血流动力学与免疫功能变化情况。结果:两组的手术时间、麻醉时间、术中出血量与术中补液量比较,差异均无统计学意义(P>0.05)。在T_0、T_(1)、T_(2)、T_(3)时,两组的HR与SpO_(2)都处于正常范围内,两组比较差异均无统计学意义(P>0.05)。术后3 d,观察组的CD4^(+)、CD8^(+)与术前1 d比较,差异均无统计学意义(P>0.05),对照组的CD4^(+)比例高于术前1 d,CD8^(+)比例低于术前1 d,差异均有统计学意义(P<0.05)。观察组不良反应发生率为6.4%,显著低于对照组的27.7%(P<0.05)。结论:全凭静脉麻醉在腹股沟疝手术患者中的应用并不会影响患者的血流动力学与免疫功能,且不影响手术与麻醉效果,不会增加术后不良反应的发生。
Objective:To explore the effect of total intravenous anesthesia on hemodynamics and immune function in patients with inguinal hernia surgery.Method:A total of 94 patients underwent inguinal hernia repair in our hospital from June 2018 to May 2020 were selected,the patients were divided into observation group and control group according to the principle of random envelope lottery,47 cases in each group.The control group was given combined intravenous anesthesia,the observation group was given total intravenous anesthesia.Compared the changes of hemodynamics and immune function of the two groups at different time points.Result:There were no significant differences in operation time,anesthesia time,intraoperative blood loss and intraoperative fluid rehydration between the two groups(P>0.05).At T_(0),T_(1),T_(2) and T_(3),HR and SpO_(2) in both groups were within the normal range,there were no statistically significant differences between the two groups(P>0.05).There were no significant differences in CD4^(+)and CD8^(+)in the observation group at postoperative 3 d compared with preoperative 1 d(P>0.05),the proportion of CD4^(+)in the control group was higher than that 1 d before surgery,the proportion of CD8^(+)was lower than that 1 d before surgery,the differences were statistical significance(P<0.05).The incidence of adverse reactions in the observation group was 6.4%,which was significantly lower than 27.7%in the control group(P<0.05).Conclusion:The application of total intravenous anesthesia in patients with inguinal hernia surgery will not affect the hemodynamics and immune function of the patients,will not affect the effect of surgery and anesthesia,it can’t add the occurrence of postoperative adverse reactions.
作者
李京洲
LI Jingzhou(Jiamusi Central Hospital,Jiamusi 154002,China)
出处
《中国医学创新》
CAS
2021年第10期126-130,共5页
Medical Innovation of China
关键词
全凭静脉麻醉
腹股沟疝
血流动力学
免疫功能
Total intravenous anesthesia
Inguinal hernia
Hemodynamics
Immune function
