摘要
目的分析腹腔镜经腹腹膜前腹股沟疝无张力修补术的临床效果。方法选取2020年4月—2022年12月在南通市通州区第二人民医院接受治疗的78例腹股沟疝患者作为研究对象,利用抽签的方式将其平均分为对照组和观察组,39例作为对照组采用传统无张力修补术治疗,其余39例作为观察组采用腹腔镜经腹腹膜前腹股沟疝无张力修补术治疗,对比两组手术时间、创口疼痛时间、术中出血量、住院时间以及术后正常活动时间等临床指标,检测两组氧化应激因子、去甲肾上腺素、白细胞介素-6等因子的变化,评估两组术后疼痛程度,统计两组并发症发生率、复发率。结果观察组手术时间、术中出血量、创口疼痛时间、住院时间、术后开始正常活动时间均优于对照组,差异有统计学意义(P<0.05)。术前,两组氧化应激因子、皮质醇、去甲肾上腺素、C反应蛋白、白细胞介素-6比较,差异无统计学意义(P>0.05)。术后24、72 h,两组总抗氧化能力、超氧化物歧化酶均较术前降低,但观察组高于对照组,差异有统计学意义(P<0.05);两组丙二醛、皮质醇、去甲肾上腺素、C反应蛋白、白细胞介素-6较术前升高,但观察组术后24、72 h低于对照组,差异有统计学意义(P<0.05)。观察组术后6、24、48、72 h的视觉模拟评分低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为7.69%,低于对照组的25.64%,差异有统计学意义(χ^(2)=4.523,P<0.05),而复发率为10.26%与对照组的7.69%比较,差异无统计学意义(χ^(2)=0.157,P>0.05)。结论与传统手术相比,腹腔镜经腹腹膜前腹股沟疝无张力修补术不仅能减少手术出血量,还可减轻机体疼痛感,减少术后并发症发生率,对机体应激反应较小,治疗效果显著。
Objective To analyze the clinical effect of laparoscopic tension-free repair of preperitoneal inguinal hernia.Methods A total of 78 patients with inguinal hernia who received treatment in Tongzhou District Second People's Hospital from April 2020 to December 2022 were selected as the research objects,and were evenly divided into control group and observation group by drawing lots.39 patients in the control group were treated with traditional tension-free repair,and the other 39 patients in the observation group were treated with laparoscopic tension-free repair of preperitoneal inguinal hernia.Clinical indexes such as operation time,wound pain time,intraoperative blood loss,hospital stay and postoperative normal activity time of the two groups were compared.The changes of oxidative stress factor,norepinephrine,interleukin-6 and other factors in the two groups were detected.The postoperative pain degree of the two groups was evaluated,and the complication rate and recurrence rate of the two groups were analyzed.Results The operation time,intraoperative blood loss,wound pain time,hospital stay and normal activity time of the observation group were all better than those of the control group,and the difference was statistically significant(P<0.05).Before surgery,there was no statistically significance in oxidative stress factor,cortisol,norepinephrine,C-reactive protein and interleukin-6 between the two groups(P>0.05).The total antioxidant capacity and superoxide dismutase of the two groups were decreased 24 and 72 hours after operation,but the observation group was higher than the control group 24 and 72 hours after surgery,and the difference was statistically significant(P<0.05).The levels of malondialdehyde,cortisol,norepinephrine,C-reactive protein and interleukin-6 in the two groups were higher than those before surgery,but the observation group was lower than the control group 24 h and 72 h after surgery,and the difference was statistically significant(P<0.05).The visual simulation scores of the observation gro
作者
王俊
曹海兵
WANG Jun;CAO Haibing(Department of Surgery,Tongzhou District Second People's Hospital,Nantong,Jiangsu Province,226300 China)
出处
《世界复合医学》
2023年第9期123-127,共5页
World Journal of Complex Medicine
