摘要
目的:观察分析三餐前短效胰岛素加甘精胰岛素和胰岛素泵短期强化治疗2型糖尿病的效果。方法:择取2019年7月-2020年6月接收的2型糖尿病患者68例,按随机数字法分为两组。参照组34例,应用胰岛素泵短期强化治疗;试验组34例,应用三餐前短效胰岛素加甘精胰岛素治疗。观察对比两组治疗前后血糖水平、血糖达标时间、胰岛素用量、低血糖发生次数及治疗费用。结果:两组治疗前空腹血糖、餐后2 h血糖水平对比差异无统计学意义(P>0.05),治疗后两组空腹血糖、餐后2 h血糖水平均较治疗前显著降低(P<0.05),但组间比较差异无统计学意义(P>0.05);两组血糖达标时间对比差异无统计学意义(P>0.05);试验组患者胰岛素用量和治疗费用均少于参照组,低血糖发生次数多于参照组,组间对比差异有统计学意义(P<0.05)。结论:三餐前短效胰岛素加甘精胰岛素及胰岛素泵短期强化治疗均可有效控制患者血糖水平,促进血糖快速达标,但三餐前短效胰岛素加甘精胰岛素治疗更有利于减少胰岛素用量,减轻患者经济压力,而胰岛素泵短期强化治疗更有利于避免或减少低血糖发生率。
Objective:To observe and analyze the efficacy on short-acting insulin before three meals plus Insulin Glargine and Insulin pump for short-term intensive treatment in type 2 diabetes mellitus.Method:A total of 68 T2DM patients admitted from July 2019 to June 2020 were randomly divided into two groups.The control group of 34 patients received short-term intensive therapy with insulin pump.Thirty-four patients in experimental group were treated with Insulin Glargine and short-acting insulin before three meals.The blood glucose level,the time to reach the target of blood glucose,the amount of insulin,the frequency of hypoglycemia and the cost of treatment were observed and compared between the two groups before and after treatment.Result:Before treatment,there was no significant difference of 2 h postprandial blood glucose fasting glucose levels between the two groups (P>0.05).After treatment,2 h postprandial blood glucose fasting glucose levels were significantly lower than before treatment in both two groups (P<0.05),but there was no significant difference between the two groups (P>0.05).There was no significant difference of time of blood glucose normalization between the two groups (P>0.05).The insulin dosage and treatment cost of the experimental group were less than those of the control group,and the occurrence times of hypoglycemia was higher than that of the control group,the differences were statistically significant (P<0.05).Conclusion:Short acting insulin plus Insulin Glargine and insulin pump short-term intensive therapy before three meals can effectively control the blood glucose level of patients and promote the blood glucose to reach the standard quickly,but short acting insulin plus Insulin Glargine before three meals is more conducive to reduce the amount of insulin and reduce the economic pressure of patients,while short-term intensive insulin pump treatment is more conducive to avoid or reduce the incidence of hypoglycemia.
作者
任碧池
罗颖
赵旋
张炫
曾晓
REN Bichi;LUO Ying;ZHAO Xuan;ZHANG Xuan;ZENG Xiao(The Third People’s Hospital of Jingzhou,Jingzhou 434000,China;不详)
出处
《中外医学研究》
2021年第10期41-43,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
基金
2015年度湖北省卫生计生指导性项目(WJ2015Z101)。
关键词
三餐前短效胰岛素
甘精胰岛素
胰岛素泵短期强化
2型糖尿病
Short-acting insulin before three meals
Insulin Glargine
Insulin pump short-term reinforcement
Type 2 Diabetes
