摘要
目的探讨糖尿病外周血管病变患者采用介入治疗的临床效果。方法回顾性分析80例合并外周血管病变的糖尿病患者的临床资料,按照随机数字表法分为观察组与对照组,各40例。对照组实施常规治疗,观察组在常规治疗基础上实施介入治疗。比较两组的临床疗效、踝肱指数、足背动脉血流量、血流动力学指标、症状评分、下肢周径差值、生活质量评分。结果观察组治疗总有效率97.50%高于对照组的82.50%,差异具有统计学意义(P<0.05)。治疗后,观察组的踝肱指数(1.19±0.17)、足背动脉血流量(0.98±0.23)m/(s·mm^(2))高于治疗前的(0.87±0.14)、(0.56±0.22)m/(s·mm^(2));对照组的的踝肱指数(1.02±0.15)、足背动脉血流量(0.76±0.21)m/(s·mm^(2))高于治疗前的(0.86±0.13)、(0.55±0.20)m/(s·mm^(2));且观察组高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组患者红细胞压积(25.69±3.87)%、红细胞沉降率(15.21±4.59)mm/h及血浆粘度(1.29±0.37)mPa·s均低于本组治疗前的(38.25±4.09)%、(28.54±6.65)mm/h、(2.41±0.53)mPa·s,对照组患者红细胞压积(32.54±4.52)%、红细胞沉降率(21.85±5.93)mm/h及血浆粘度(1.76±0.43)mPa·s均低于本组治疗前的(38.17±4.13)%、(28.23±6.31)mm/h、(2.45±0.59)mPa·s,且观察组均低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者疼痛、麻木、发绀、皮肤低温症状评分低于治疗前,且观察组均低于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组患者患-健侧大腿周径差值(1.42±0.29)cm、患-健侧小腿周径差值(1.40±0.24)cm均低于本组治疗前的(2.04±0.37)、(1.76±0.32)cm,对照组患者患-健侧大腿周径差值(1.72±0.30)cm、患-健侧小腿周径差值(1.68±0.27)cm均低于本组治疗前的(2.07±0.35)、(1.79±0.30)cm,且观察组低于对照组,差异均具有统计学意义(P<0.05)。治疗后,两组患者生理领域、心理领域、环境领域、社会关系领域评�
Objective To discuss the clinical effect of interventional therapy for patients with diabetic peripheral vascular disease.Methods A total of 80 patients with diabetic peripheral vascular disease were divided into observation group and control group according to random numerical table,with 40 cases in each group.The control group received conventional therapy,and the observation group received interventional therapy based on conventional therapy.The clinical efficacy,ankle brachial index,blood flow of dorsalis pedis artery,hemodynamic parameters,symptom score,lower limb circumference difference and quality of life score were compared between the two groups.Results The total effective rate 97.50%of the observation group was higher than 82.50%of the control group,and the difference was statistically significant(P<0.05).After treatment,the ankle brachial index(1.19±0.17)and blood flow of dorsalis pedis artery(0.98±0.23)m/(s·mm^(2))of the observation group were higher than(0.87±0.14)and(0.56±0.22)m/(s·mm^(2))before treatment;the ankle brachial index(1.02±0.15)and blood flow of dorsalis pedis artery(0.76±0.21)m/(s·mm^(2))of the control group were higher than(0.86±0.13)and(0.55±0.20)m/(s·mm^(2))before treatment;the above indicators of the observation group were higher than those of the control group.All the difference was statistically significant(P<0.05).After treatment,the hematocrit(25.69±3.87)%,erythrocyte sedimentation rate(15.21±4.59)mm/h and plasma viscosity(1.29±0.37)m Pa·s were lower than(38.25±4.09)%,(28.54±6.65)mm/h and(2.41±0.53)m Pa·s before treatment;the hematocrit(32.54±4.52)%,erythrocyte sedimentation rate(21.85±5.93)mm/h and(1.76±0.43)m Pa·s of the control group were lower than(38.17±4.13)%,(28.23±6.31)mm/h and(2.45±0.59)m Pa·s before treatment;the above indicators of the observation group were lower than those of the control group.All the difference was statistically significant(P<0.05).After treatment,the symptoms scores of pain,numbness,cyanosis and skin hypothermia of the
作者
张文
ZHANG Wen(Department of General Surgery,Liuhe Hospital Affiliated to Yangzhou University Medical School,Nanjing 211500,China)
出处
《中国现代药物应用》
2021年第9期1-4,共4页
Chinese Journal of Modern Drug Application
关键词
糖尿病
外周血管病变
介入治疗
Diabetes mellitus
Peripheral vascular disease
Interventional therapy
