摘要
泛素结合酶E2C(UBE2C)属于E2酶家族中的成员,它在泛素-蛋白酶体途径中具有重要的生物学作用,泛素结合酶E2C是细胞周期进展和周期蛋白降解所必需的。泛素结合酶E2C在多种肿瘤组织中高度表达,与肿瘤的发生发展密切相关。本文就结合国内外最新报道,对泛素结合酶E2C与肿瘤相关性研究进展作一综述。
Ubiquitin binding enzyme 2C(UBE2C)is a member of the E2 enzyme family.It plays an important role in the ubiquitin proteasome pathway.UBE2C is essential for cell cycle progression and cyclin degradation.UBE2C is highly expressed in a variety of tumor tissues,which is closely related to the occurrence and development of tumor.In this paper,we reviewed the research progress of the relationship between UBE2C and tumors.
作者
杨兰
贾霄
姜奕彤
崔琪
刘光赐
何颖红
Yang Lan;Jia Xiao;Jiang Yitong;Cui Qi;Liu Guangci;He Yinghong(School of Basic Medicine,Dali University,Dali 671000;Key Laboratory of University Cell Biology,Yunnan Province,Dali 671000,China)
出处
《广东化工》
CAS
2021年第4期111-111,110,共2页
Guangdong Chemical Industry
