摘要
目的:分析本院实施会诊干预制度前后特殊使用级抗菌药物的使用情况,为促进特殊使用级抗菌药物合理使用提供参考。方法:回顾性收集本院2017~2019年抗菌药物和特殊使用级抗菌药物的用量、销售金额、使用率、抗菌药物使用强度(AUD)等相关指标;对比会诊干预制度实施前后抗菌药物的使用情况,以及住院患者的常见病原菌。结果:本院住院患者AUD由2017年的35.99 DDDs/100人/天上升至2019年的60.26 DDDs/100人/天;特殊使用级AUD由2017年的25.15 DDDs/100人/天下降至2019年的12.32 DDDs/100人/天;住院患者特殊使用级抗菌药物使用金额占比由2017年的71.15%下降至2019年的38.94%;近年本院主要病原菌为金黄色葡萄球菌、大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌和鲍曼不动杆菌。结论:本院自实施会诊干预制度后特殊使用级抗菌药物的滥用情况得到了有效控制,但非特殊使用级抗菌药物的使用仍需加强监管,应严控抗菌药物的不合理使用。
Objective:To analyze the usage of special-use antibacterial drugs before and after the implementation of the consultation intervention system in our orthopedic hospital,and provide references for promoting the rational use of special-use antibacterial drugs.Methods:The data about consumption,sales amount,usage rate,antibiotics use density(AUD)and other relevant indicators of antibacterial drugs and special-use antibacterial drugs in orthopedic hospital from 2017 to 2019 were collected.The usage of antibiotics before and after the implementation of the consultation intervention system and the common pathogens in hospitalized patients were compared.Results:AUD inpatients in orthopedic hospital rose from 35.99 DDDs/100 persons/day in 2017 to 60.26 DDDs/100 persons/day in 2019.The density of special-use AUD decreased from 25.15 DDDs/100 persons/day in 2017 to 12.32 DDDs/100 persons/day in 2019.The proportion of special-use antibacterial drugs used by inpatients dropped from 71.15%in 2017 to 38.94%in 2019.In recent years,the main pathogens in orthopedic hospital were Staphylococcus aureus,Escherichia coli,Klebsiella pneumoniae,Pseudomonas aeruginosa and Acinetobacter baumanii.Conclusion:Since the implementation of the consultation intervention system in our hospital,the abuse of special-use antibacterial drugs has been effectively controlled.However,the supervision on the use of non-special-use antibacterial drugs still needs to be strengthened and the unreasonable use of antibacterial drugs should be strictly controlled.
作者
姜立群
鲁燕侠
JIANG Li-qun;LU Yan-xia(Department of Pharmacy,Shanghai Kaiyuan Orthopaedic Hospital,Shanghai 200129,China;Department of Pharmacy,Medical Supplies Center of Chinese PLA General Hospital,Beijing 100039,China)
出处
《中国合理用药探索》
CAS
2021年第4期19-24,共6页
Chinese Journal of Rational Drug Use
关键词
会诊干预
特殊使用级抗菌药物
使用金额
抗菌药物使用强度
排序比
consultation intervention
special-use antibacterial drugs
usage cost
antibiotics use density
sort ratio
