摘要
中药多基原现象极为常见,尽管多基原中药材的不同基原之间在性状特征、显微特征、理化特征、分子水平等方面均存在差异,但一般差异不显著,这给中药材质量控制标准的制定带来了挑战。现统计了2020年版《中国药典》收载的多基原中药材,从性状、显微、理化、分子等4个方面对多基原中药材的药典鉴别方法和文献鉴别方法的研究进展进行综述,总结了现阶段多基原中药材鉴别存在的问题并提出解决策略,为建立多基原中药材的综合鉴别体系,制定合理、可行的多基原中药材质量标准提供依据。
The phenomenon of multiple sources of traditional Chinese medicines exists universally.Although there are differences in the characteristics,microscopic characteristics,physicochemical characteristics and molecular level among different sources,the differences generally appear not that significant,which brings challenges to the formulation of quality control standards for Chinese medicinal materials.Thus statistics of multi-source Chinese medicinal materials contained in the Chinese Pharmacopoeia(2020 edition)were made in this paper.Then,this paper reviewed the research progress in pharmacopoeia and literature identification method of multi-source Chinese medicinal materials from character identification,microscopic identification,physicochemical identification and molecular identification,and also summarized the problems existing in the identification of multi-source Chinese medicinal materials and put forward the strategies.All those were aimed to establish multi-source Chinese medicinal materials comprehensive identification system and to provide the basis for formulating reasonable and feasible quality standards of multi-source Chinese medicinal materials.
作者
王雨青
刘金凤
于佳禾
石晋丽
WANG Yuqing;LIU Jinfeng;YU Jiahe;SHI Jinli(School of Chinese Medica Materia,Beijing University of traditional Chinese Medicine,Beijing,102488 P.R.China)
出处
《华西药学杂志》
CAS
CSCD
2021年第2期214-222,共9页
West China Journal of Pharmaceutical Sciences
基金
国家自然科学基金资助项目(批准号:81673560)
北京市技术开发类横向课题(2017110031015577)。
关键词
多基原
中药材
鉴别
中国药典
分子水平
DNA条形码
指纹图谱
质量标准
Multi-source
Chinese medicinal materials
Identification
Chinese Pharmacopoeia
Molecular level
DNA barcoding
Fingerprint
Quality standards
